中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2009年
21期
1490-1492
,共3页
荧光素血管造影术%副作用
熒光素血管造影術%副作用
형광소혈관조영술%부작용
Fluoreacein angiography%Adverse effects
目的 观察特殊人群荧光素眼底血管造影的不良反应发生率及相关因素.方法 使用海德堡眼底血管造影机对256例特殊人群进行造影,按体重注射荧光素钠造影剂,观察记录不良反应的情况.特殊人群是指有符合下列条件之一的患者:(1)有药物过敏史者;(2)有重要内脏器官疾病者;(3)首次检查有恶心、呕吐、瘙痒等轻度反应但需再次检查者;(4)年龄≥80岁身体健康者.结果 256例特殊人群造影出现不良反应69例,占本组患者的27.0%.造影的不良反应多为轻中度.既往有药物过敏史者73例中,有10例出现恶心呕吐,喷嚏,瘙痒等反应,占该组患者的13.7%;有重要内脏器官疾病者78例中,4例有恶心呕吐反应,占该组患者的5.1%;首次检查有恶心、呕吐、瘙痒等反应但需再次检查者56例中,有54例均有不同程度的不良反应发生,占该组患者的96.4%;年龄≥80岁身体健康者49例中有l例发生恶心反应,占该组患者的2.0%.结论 FFA检查对这类特殊人群是一项安全检查,特殊人群造影的不良反应一般是轻中度,其不良反应发生率与健康人群使用荧光素钠造影不良反应相似.仔细观察患者,加强防范和抢救措施,对提高特殊人群血管造影的安全性有重要意义.
目的 觀察特殊人群熒光素眼底血管造影的不良反應髮生率及相關因素.方法 使用海德堡眼底血管造影機對256例特殊人群進行造影,按體重註射熒光素鈉造影劑,觀察記錄不良反應的情況.特殊人群是指有符閤下列條件之一的患者:(1)有藥物過敏史者;(2)有重要內髒器官疾病者;(3)首次檢查有噁心、嘔吐、瘙癢等輕度反應但需再次檢查者;(4)年齡≥80歲身體健康者.結果 256例特殊人群造影齣現不良反應69例,佔本組患者的27.0%.造影的不良反應多為輕中度.既往有藥物過敏史者73例中,有10例齣現噁心嘔吐,噴嚏,瘙癢等反應,佔該組患者的13.7%;有重要內髒器官疾病者78例中,4例有噁心嘔吐反應,佔該組患者的5.1%;首次檢查有噁心、嘔吐、瘙癢等反應但需再次檢查者56例中,有54例均有不同程度的不良反應髮生,佔該組患者的96.4%;年齡≥80歲身體健康者49例中有l例髮生噁心反應,佔該組患者的2.0%.結論 FFA檢查對這類特殊人群是一項安全檢查,特殊人群造影的不良反應一般是輕中度,其不良反應髮生率與健康人群使用熒光素鈉造影不良反應相似.仔細觀察患者,加彊防範和搶救措施,對提高特殊人群血管造影的安全性有重要意義.
목적 관찰특수인군형광소안저혈관조영적불량반응발생솔급상관인소.방법 사용해덕보안저혈관조영궤대256례특수인군진행조영,안체중주사형광소납조영제,관찰기록불량반응적정황.특수인군시지유부합하렬조건지일적환자:(1)유약물과민사자;(2)유중요내장기관질병자;(3)수차검사유악심、구토、소양등경도반응단수재차검사자;(4)년령≥80세신체건강자.결과 256례특수인군조영출현불량반응69례,점본조환자적27.0%.조영적불량반응다위경중도.기왕유약물과민사자73례중,유10례출현악심구토,분체,소양등반응,점해조환자적13.7%;유중요내장기관질병자78례중,4례유악심구토반응,점해조환자적5.1%;수차검사유악심、구토、소양등반응단수재차검사자56례중,유54례균유불동정도적불량반응발생,점해조환자적96.4%;년령≥80세신체건강자49례중유l례발생악심반응,점해조환자적2.0%.결론 FFA검사대저류특수인군시일항안전검사,특수인군조영적불량반응일반시경중도,기불량반응발생솔여건강인군사용형광소납조영불량반응상사.자세관찰환자,가강방범화창구조시,대제고특수인군혈관조영적안전성유중요의의.
Objective To determine the incidence rate and correlation factors of the adverse reactions during fluorescence fundus angiography (FFA) in special patients. Methods 256 special patients were performed FFA with Heidelberg Retinal Angiography. Fluorescein Sodium was given according to the body weight and adverse reactions during FFA were observed. The special patients enrolled in this study include those with drug allergy history, system disease, light adverse reactions such as nausea, vomiting and pruritus during the fist FFA or patients over 80 years old. Results Adverse reactions were observed in 69 of 256 (27.0%) cases and the majority is at a mild to moderate degree. Nausea, sneezing, vomiting or pruritus occurred in 10 of 73 (13.7%) patients with drug allergy history. Nausea or vomiting occurred in 4 of 78 (5.1%) patients with systemic diseases. Different degrees of adverse reactions occurred in 54 of 56 (94.6%) cases who had nausea, vomiting or pruritus during the first FFA. Nausea occurred in 1 of 49 (2.0%) patients over 80 years old. Conclusion FFA is a safe examination for the above special patients. The incidence rate of adverse reaction due to FFA in these special patients is similar to that in the healthy population. Observing the patients closely and strengthening the containment and salvage measures are important to improve the safety of FFA in these special patients.
