中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
19期
2628-2630
,共3页
焦虑症%自主神经功能%心率%心率变异性
焦慮癥%自主神經功能%心率%心率變異性
초필증%자주신경공능%심솔%심솔변이성
Anxiety neurosis%Autonomic nervous function%Heart rate%Heart rate variability
目的 探讨焦虑症患者心率变异性与自主神经功能的相关性,为焦虑症患者心身疾病的防治提供理论参考.方法 对90例广泛性焦虑症、惊恐障碍患者和90例健康查体者进行心理问卷测试,并采用汉密顿焦虑量表(HAMA)和汉密顿抑郁量表(HAMD)进行焦虑和抑郁症状的评定,采用24 h动态心电图记录监测心率及心率变异性指标(SDNN、SDANN、RMSSD、PNN50).结果 焦虑症(GAD)组平均心率显著高于对照组,两组差异均有统计学意义(P<0.05);心率变异性各指标均显著低于对照组,两组差异均有统计学意义(P<0.05);GAD组的各心率变异性指标均显著低于对照组,而惊恐障碍(PD)组的各心率变异性指标均显著低于GAD组,差异均有统计学意义(P<0.05).结论 焦虑症患者存在较高水平的交感神经活动功能,自主神经功能紊乱,且PD患者的交感神经活动功能增高,自主神经功能紊乱程度增加.
目的 探討焦慮癥患者心率變異性與自主神經功能的相關性,為焦慮癥患者心身疾病的防治提供理論參攷.方法 對90例廣汎性焦慮癥、驚恐障礙患者和90例健康查體者進行心理問捲測試,併採用漢密頓焦慮量錶(HAMA)和漢密頓抑鬱量錶(HAMD)進行焦慮和抑鬱癥狀的評定,採用24 h動態心電圖記錄鑑測心率及心率變異性指標(SDNN、SDANN、RMSSD、PNN50).結果 焦慮癥(GAD)組平均心率顯著高于對照組,兩組差異均有統計學意義(P<0.05);心率變異性各指標均顯著低于對照組,兩組差異均有統計學意義(P<0.05);GAD組的各心率變異性指標均顯著低于對照組,而驚恐障礙(PD)組的各心率變異性指標均顯著低于GAD組,差異均有統計學意義(P<0.05).結論 焦慮癥患者存在較高水平的交感神經活動功能,自主神經功能紊亂,且PD患者的交感神經活動功能增高,自主神經功能紊亂程度增加.
목적 탐토초필증환자심솔변이성여자주신경공능적상관성,위초필증환자심신질병적방치제공이론삼고.방법 대90례엄범성초필증、량공장애환자화90례건강사체자진행심리문권측시,병채용한밀돈초필량표(HAMA)화한밀돈억욱량표(HAMD)진행초필화억욱증상적평정,채용24 h동태심전도기록감측심솔급심솔변이성지표(SDNN、SDANN、RMSSD、PNN50).결과 초필증(GAD)조평균심솔현저고우대조조,량조차이균유통계학의의(P<0.05);심솔변이성각지표균현저저우대조조,량조차이균유통계학의의(P<0.05);GAD조적각심솔변이성지표균현저저우대조조,이량공장애(PD)조적각심솔변이성지표균현저저우GAD조,차이균유통계학의의(P<0.05).결론 초필증환자존재교고수평적교감신경활동공능,자주신경공능문란,차PD환자적교감신경활동공능증고,자주신경공능문란정도증가.
Objective To study the correlation of heart rate variability(HRV) and autonomic nervous function in patients with anxiety neurosis, and provide evidence for prevention and treatment of anxiety disorder. Methods 90 patients with generalized anxiety disorder(GAD) and panic disorder(PD) and 90 healthy persons were tested by psychological questionnaire,the anxiety and depression were assessed by HAMA and HAMD. The average heart rate and HRV index were monitored by 24-hour ambulatory ECG. Results The average heart rate of the anxiety group was higher than the control group, compared with the control group the difference was significant ( P < 0. 05 ); The HRV parameters of the anxiety group were lower than the control group, compared with the control group the difference was significant( P < 0. 05 ) ;The HRV parameters of the GAD group were lower than the control group, the HRV parameters of the PD group were lower than the GAD group, the difference was significant ( P < 0. 05 ). Conclusion The patients with anxiety neurosis had high sympathetic nerve activity function and autonomic dysfunction, the PD patients had higher sympathetic nerve activity function and autonomic dysfunction than the GAD patients.
