CAJ | 학술논문

在吖啶磺酰胺分子中引入杂环安替比林吸电性基团,合成了N-对甲基苯磺酰基-N-(4-安替比林)-10-甲基吖啶-9-磺酰胺三氟甲基磺酸鎓盐.最终产物与未甲基化的前体分别与模型化合物N-对甲基苯磺酰基-N-苯基-10-甲基吖啶-9-酰胺三氟甲基磺酸鎓盐及其前体的紫外-可见吸收光谱(UV)、荧光光谱(FL)进行比较.结果表明,引入杂环安替比林使吖啶磺酰胺的UV和FL谱发生了变化,尤其是FL谱的最大激发与发射峰的位置比相应的模型化合物大幅蓝移.最终产物及其前体的最大λex分别为268和274 nm; λem分别为321和327 nm.而模型化合物及前体最大λex分别为365和359 nm; λem分别为504和440 nm.H2O2引发的目标产物的化学发光(CL)在1.1 s完成;化学发光量子产率与模型化合物相当,是Luminol的化学发光效率的5.6倍.
재아정광선알분자중인입잡배안체비림흡전성기단,합성료N-대갑기분광선기-N-(4-안체비림)-10-갑기아정-9-광선알삼불갑기광산옹염.최종산물여미갑기화적전체분별여모형화합물N-대갑기분광선기-N-분기-10-갑기아정-9-선알삼불갑기광산옹염급기전체적자외-가견흡수광보(UV)、형광광보(FL)진행비교.결과표명,인입잡배안체비림사아정광선알적UV화FL보발생료변화,우기시FL보적최대격발여발사봉적위치비상응적모형화합물대폭람이.최종산물급기전체적최대λex분별위268화274 nm; λem분별위321화327 nm.이모형화합물급전체최대λex분별위365화359 nm; λem분별위504화440 nm.H2O2인발적목표산물적화학발광(CL)재1.1 s완성;화학발광양자산솔여모형화합물상당,시Luminol적화학발광효솔적5.6배.
By introducing an electro-withdrawing antipyrine group, N-(p-toluenesulfonyl)-N-(4-antipyrine)-10-methylacridinium-9-carboxamide triflate was prepared. The UV, FL and CL properties of the target compound and of its precursor were investigated by comparing with those of the model compound N-(p-toluenesulfonyl)-N-phenyl-10-methylacridinium-9-carboxamide triflate and the corresponding precursor respectively. The results show that acridine sulfonamide with a heterocyclic antipyrine group exhibits blue shift of both UV absorption and of maximum excitation wavelength(λex) and emission wavelength(λem) in FL spectra, comparing with the corresponding model compound. The λex of the final target and its precursor are 268 and 274 nm, respectively; and the λem are 321 and 327 nm, respectively, while λex of the model compound and its unmethylated precursor are 365 and 359 nm, respectively; and the λem are 504 and 440 nm, respectively. Moreover, the chemiluminescence of the final target compound triggered by H2O2 could finish within 1.1 s; and the quantum yield is similar to that of the model compound, being 5.6 times high as that of luminol.