国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2012年
3期
176-178
,共3页
轮状病毒%感染%蒙脱石散%山莨菪碱
輪狀病毒%感染%矇脫石散%山莨菪堿
륜상병독%감염%몽탈석산%산랑탕감
Rotaviraus%Infections%Montmorillonite powder%Anisodamine
目的 探讨蒙脱石散联合山莨菪碱治疗轮状病毒性肠炎的疗效.方法 选取2008年1月至2010年9月在我院就诊的轮状病毒性肠炎患儿182例,根据是否进行蒙脱石散联合山莨菪碱治疗分为对照组81例,治疗组101例.对照组给予利巴韦林(10～ 15 mg·kg-1 ·d-1)抗病毒及补液等治疗；治疗组在对照组基础上加用蒙脱石散(＜1岁者1g,3次/d,＞1岁者1.5g,3次/d,首次加倍)联合山莨菪碱(0.1 ～0.3 mg/kg)治疗.以粪便次数减少、性状转好及全身症状缓解为疗效评判标准.结果 治疗组的总有效率达92.08％(93例),明显高于对照组的67.90％(55例),且差异有统计学意义(x2=19.152,P＜ 0.01).治疗组退热时间和止泻时间分别为(2.78±0.85)d和(3.06±1.58)d,明显短于对照组的(3.65±0.76)d和(5.04±1.88)d,两组比较差异有统计学意义(t=6.447、7.719,P＜0.01).结论 蒙脱石散联合山莨菪碱治疗轮状病毒疗效明显,值得临床推广应用.
目的 探討矇脫石散聯閤山莨菪堿治療輪狀病毒性腸炎的療效.方法 選取2008年1月至2010年9月在我院就診的輪狀病毒性腸炎患兒182例,根據是否進行矇脫石散聯閤山莨菪堿治療分為對照組81例,治療組101例.對照組給予利巴韋林(10～ 15 mg·kg-1 ·d-1)抗病毒及補液等治療；治療組在對照組基礎上加用矇脫石散(＜1歲者1g,3次/d,＞1歲者1.5g,3次/d,首次加倍)聯閤山莨菪堿(0.1 ～0.3 mg/kg)治療.以糞便次數減少、性狀轉好及全身癥狀緩解為療效評判標準.結果 治療組的總有效率達92.08％(93例),明顯高于對照組的67.90％(55例),且差異有統計學意義(x2=19.152,P＜ 0.01).治療組退熱時間和止瀉時間分彆為(2.78±0.85)d和(3.06±1.58)d,明顯短于對照組的(3.65±0.76)d和(5.04±1.88)d,兩組比較差異有統計學意義(t=6.447、7.719,P＜0.01).結論 矇脫石散聯閤山莨菪堿治療輪狀病毒療效明顯,值得臨床推廣應用.
목적 탐토몽탈석산연합산랑탕감치료륜상병독성장염적료효.방법 선취2008년1월지2010년9월재아원취진적륜상병독성장염환인182례,근거시부진행몽탈석산연합산랑탕감치료분위대조조81례,치료조101례.대조조급여리파위림(10～ 15 mg·kg-1 ·d-1)항병독급보액등치료；치료조재대조조기출상가용몽탈석산(＜1세자1g,3차/d,＞1세자1.5g,3차/d,수차가배)연합산랑탕감(0.1 ～0.3 mg/kg)치료.이분편차수감소、성상전호급전신증상완해위료효평판표준.결과 치료조적총유효솔체92.08％(93례),명현고우대조조적67.90％(55례),차차이유통계학의의(x2=19.152,P＜ 0.01).치료조퇴열시간화지사시간분별위(2.78±0.85)d화(3.06±1.58)d,명현단우대조조적(3.65±0.76)d화(5.04±1.88)d,량조비교차이유통계학의의(t=6.447、7.719,P＜0.01).결론 몽탈석산연합산랑탕감치료륜상병독료효명현,치득림상추엄응용.
Objective To observe the therapeutic effect of montmorillonite powder and anisodamine in treating rotavirus enteritis.Methods One hundred and eighty-two rotavims enteritis children treated in our hospital from January 2008 to September 2010 were divided into two groups,there were 81 cases in control group and 101 cases in treatment group.Children in control group were treated with ribavirin( 10-15 mg· kg-1 · d-1 ) and liquid supplement,children in treatmert group were treated with montmorillonite powder( ＜ 1 years old,1g,3 times a day; ＞ 1 years old,1.5 g,3 times a day; double for the first time) and anisodamine(0.1-0.3 mg/kg) on the basis of the treatment of control group.The therapeutic effects were observed.Results The total effective rate in treatment group(92.08％,93 cases) was much higher than that in control group(67.90％,55 cases),and there was a statistical difference between the two groups ( x2 =19.152,P ＜ 0.01 ).The defervesce time and antidiarrheal time in treatment group were (2.78 ± 0.85) and (3.06 ± 1.58 ) days,and in control group were ( 3.65 ± 0.76 ) and ( 5.04 ± 1.88 ) days,there were statistical differences between the two groups(t =6.447,7.719,P ＜0.01).Conclusions Montmorillonite powder and anisodamine are effective in treating rotavirus enteritis,and it is worthy to be used.
