CAJ | 학술논문

目的:探索良好的肠吻合术式,以防止肠闭锁之小口径肠管吻合术后吻合口梗阻的发生.方法:改良肠单层吻合术与全层内翻吻合术进行动物实验比较,并临床应用.结果:切片观察示吻合口粘膜连续性恢复好,粘膜缺损少,粘膜下移少而轻,粘膜下层对合满意.与全层内翻吻合比较有统计学差异.术后2周吻合口标本羟脯氨酸含量(代表胶原含量)实验组与对照组分别为43.527 μg/mg干重和41.423μg/mg干重(P＞0.05).7例肠闭锁患儿手术效果满意.结论:改良肠单层吻合术不仅简便省时,而且有利于吻合口愈合,防止吻合口梗阻发生,尤其适用于小口径肠管.
목적:탐색량호적장문합술식,이방지장폐쇄지소구경장관문합술후문합구경조적발생.방법:개량장단층문합술여전층내번문합술진행동물실험비교,병림상응용.결과:절편관찰시문합구점막련속성회복호,점막결손소,점막하이소이경,점막하층대합만의.여전층내번문합비교유통계학차이.술후2주문합구표본간포안산함량(대표효원함량)실험조여대조조분별위43.527 μg/mg간중화41.423μg/mg간중(P＞0.05).7례장폐쇄환인수술효과만의.결론:개량장단층문합술불부간편성시,이차유리우문합구유합,방지문합구경조발생,우기괄용우소구경장관.
Objective:To find a way of intestinal anastomosis to reduce the incidence of anastomosis obstruction in the treatment of neonatal intestinal atresia.Methods:The modified singlelayer intestinal anastomosis was performed on and compared with the two-layer intestinal anastomosis in dogs.The some anastomosis was also performed on 7 neonates with intestinal atresia.The anastomosis line of the two methods were observed under microscope.Results:Two weeks after the experiments,the hydroxyproline concentrations(standing for collagen concentration)in the suture lines were 43.527 μg/mg dry weight and 41.423 μg/mg dry weight in the modified single-layer suture group and two-layer suture group respectively.Seven newborns with intestinal atresia were operated by the modified single-layer suture method without stenosis or leakage.Conclusions:The modified single-layer anastomosis is easy,time-saving and preventing early obstruction following the anastomosis of tiny calibre of neonatal intestine