中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
8期
1013-1015
,共3页
脑梗塞%低温,人工
腦梗塞%低溫,人工
뇌경새%저온,인공
Brain infarction%Hypothermia,induced
目的 观察局部亚低温治疗急性脑梗死的临床效果.方法 99例急性脑梗死患者按单双日随机分为亚低温组(52例)和常温组(47例).两组均给予常规治疗,亚低温组加用头部亚低温治疗,观察两组的日常生活能力(ADL)、欧洲卒中评分(ESS)和临床疗效.结果 亚低温组治疗后30 d时ESS为(74.4±13.8)分明显高于常温组(65.0±17.6)(t=3.121,P＜0.01),ADL治疗后10 d、30 d、90 d分别为(39.2±32.2)、(59.3±29.7)、(64.0±31.5)分高于常温组的(23.9±19.8)、(49.3±27.3)、(56.0±30.1)分(t=2.611～2.736,P＜0.05～0.01);亚低温组总有效率(78.8%)比常温组(46.7%)高(x~2=10.953,P＜0.01).结论 局部亚低温治疗急性脑梗死有助于神经功能的恢复,提高生存质量,减少经济和社会负担.
目的 觀察跼部亞低溫治療急性腦梗死的臨床效果.方法 99例急性腦梗死患者按單雙日隨機分為亞低溫組(52例)和常溫組(47例).兩組均給予常規治療,亞低溫組加用頭部亞低溫治療,觀察兩組的日常生活能力(ADL)、歐洲卒中評分(ESS)和臨床療效.結果 亞低溫組治療後30 d時ESS為(74.4±13.8)分明顯高于常溫組(65.0±17.6)(t=3.121,P＜0.01),ADL治療後10 d、30 d、90 d分彆為(39.2±32.2)、(59.3±29.7)、(64.0±31.5)分高于常溫組的(23.9±19.8)、(49.3±27.3)、(56.0±30.1)分(t=2.611～2.736,P＜0.05～0.01);亞低溫組總有效率(78.8%)比常溫組(46.7%)高(x~2=10.953,P＜0.01).結論 跼部亞低溫治療急性腦梗死有助于神經功能的恢複,提高生存質量,減少經濟和社會負擔.
목적 관찰국부아저온치료급성뇌경사적림상효과.방법 99례급성뇌경사환자안단쌍일수궤분위아저온조(52례)화상온조(47례).량조균급여상규치료,아저온조가용두부아저온치료,관찰량조적일상생활능력(ADL)、구주졸중평분(ESS)화림상료효.결과 아저온조치료후30 d시ESS위(74.4±13.8)분명현고우상온조(65.0±17.6)(t=3.121,P＜0.01),ADL치료후10 d、30 d、90 d분별위(39.2±32.2)、(59.3±29.7)、(64.0±31.5)분고우상온조적(23.9±19.8)、(49.3±27.3)、(56.0±30.1)분(t=2.611～2.736,P＜0.05～0.01);아저온조총유효솔(78.8%)비상온조(46.7%)고(x~2=10.953,P＜0.01).결론 국부아저온치료급성뇌경사유조우신경공능적회복,제고생존질량,감소경제화사회부담.
Objective To explore the therapeutic effects of local mild hypothermia for acute cerebral infarction(ACI). Methods 99 hospitalized patients with ACI form January 2006 to July 2009 were randomly divided into mild hypotherrmia group(therapy group,n =52) and control group(n =47). All the patients were treated with routine medication,while those in therapy group patients were aslo treated local mild hypothermia. Before treatment,the 10th and 30th day after treatment ,the neurological deficits and activity of daily living(ADL) were evaluated according to European Stroke Scale(ESS) and Barthel Index respectively,and were evaluated according to Barthel Index on the 90th day. Results On the 10th and 30th day the increase rate of ESS was evaluated. On the 30th day,there was significant difference between the therapy group (74. 4 ± 13. 8) and controll group (65.0 ± 17.6) (t = 3. 121,P ＜ 0.01).On the 10th and 30th and 90th day the improvement of ADL was observed. The increase rate of ADL was(39.2 ±32. 2,59.3 ±29. 7,64. 0 ±31.5) in the therapy group and(23.9 ± 19. 8,49. 3 ±27. 3,56. 0 ± 30. 1) in the controll group (t = 2.611 ～ 2.73.6, P ＜ 0.05 ～ 0.01). The effective rate of the therapy group was 78. 8%, and the effective rate of the controll group was 46. 7%. There was significant difference between the therapy group and the controll groups (x~2 = 10. 953, P ＜ 0.01). Conclusion The local mild hypothermia is more effective than those in the controll group for ACI.
