CAJ | 학술논문

近年来,阿司匹林抵抗现象越来越引起重视.研究人员已从多个方面对这种重要现象的机制进行了探索,包括患者依从性、实验室检测方法、阿司匹林剂量、遗传学、药物相互作用等；并提出了相应的管理方法,如提高患者依从性、避免药物相互作用、调整药物剂量、加用其他有潜在应用价值的抗血小板药等.文章对阿司匹林抵抗机制的研究进展进行了综述.
근년래,아사필림저항현상월래월인기중시.연구인원이종다개방면대저충중요현상적궤제진행료탐색,포괄환자의종성、실험실검측방법、아사필림제량、유전학、약물상호작용등；병제출료상응적관리방법,여제고환자의종성、피면약물상호작용、조정약물제량、가용기타유잠재응용개치적항혈소판약등.문장대아사필림저항궤제적연구진전진행료종술.
In recent years,more and more attention has been given to aspirin resistance.Researchers have explored the mechanisms of this important phenomenon from several aspects,including patient compliance,laboratory tests,aspirin dose,genetics,and drug interactions.Many appropriate management methods of aspirin resistance have been proposed,such as improving patient compliance,avoiding drug interactions,adjusting dose,and adding other antiplatelet drugs with potential application value.This article reviews the advances in research on the mechanisms of aspirin resistance.