CAJ | 학술논문

目的探讨血红蛋白和铁蛋白水平与原发性不宁腿综合征(RLS)发病之间的关系.方法对35例原发性不宁腿综合征患者(RLS组)及对照组20例失眠患者的血红蛋白及铁蛋白水平进行检测并行统计学比较.结果 RLS组患者血清铁蛋白水平为(89.77±48.52)μg/L,对照组为(123.36±35.06)μg/L,RLS组较对照组血清铁蛋白水平低,差异有统计学意义(t=-2.713,P<0.01),而血红蛋白水平RLS组为(142.77±11.79)g/L,对照组为(139.05±12.33)g/L,2组相比差异无统计学意义(t=1.108,P>0.05).结论血清铁蛋白的降低可能是原发性不宁腿综合征的危险因素之一,而血红蛋白水平可能与原发性不宁腿综合征无关.
목적 탐토혈홍단백화철단백수평여원발성불저퇴종합정(RLS)발병지간적관계.방법 대35례원발성불저퇴종합정환자(RLS조)급대조조20례실면환자적혈홍단백급철단백수평진행검측병행통계학비교.결과 RLS조환자혈청철단백수평위(89.77±48.52)μg/L,대조조위(123.36±35.06)μg/L,RLS조교대조조혈청철단백수평저,차이유통계학의의(t=-2.713,P<0.01),이혈홍단백수평RLS조위(142.77±11.79)g/L,대조조위(139.05±12.33)g/L,2조상비차이무통계학의의(t=1.108,P>0.05).결론 혈청철단백적강저가능시원발성불저퇴종합정적위험인소지일,이혈홍단백수평가능여원발성불저퇴종합정무관.
Objective To investigate the association of serum ferritin and hemoglobin with the pathogenesis of primary restless legs syndrome(RLS). Methods Thirty-five patients with primary restless legs syndrome and twenty insomnia controls were included in this study. The level of serum ferritin and hemoglobin were measured, and the data have been analyzed using t-test. Results The level of serum ferritin in the primary RLS patients (89.77μg/L (SD:48.52)) was significantly lower than in the contruls (123.36 μg/L (SD:35.06)) (t=-2.713,P <0.01), whereas the level of hemoglobin have no statistical difference between the RLS group (142.77 g/L (SD: 11.79)) and the control group (139.05 g/L (SD: 12.33)) (t = 1.108, P > 0.05). Conclu-sions The decrease of serum ferritin may be a risk factor of primary restless legs syndrome, but the level of hemo-globin is not associated with primary restless legs syndrome.