中国寄生虫学与寄生虫病杂志
中國寄生蟲學與寄生蟲病雜誌
중국기생충학여기생충병잡지
CHINESE JOURNAL OF PARASITOLOGY AND PARASITIC DISEASES
2008年
4期
245-252
,共8页
黄燕%Heath D David%杨文%邱加闽%陈兴旺%杨筠%王谦%李调英%肖永富%邱东川%肖宁%陈发喜%格桑%色多
黃燕%Heath D David%楊文%邱加閩%陳興旺%楊筠%王謙%李調英%肖永富%邱東川%肖寧%陳髮喜%格桑%色多
황연%Heath D David%양문%구가민%진흥왕%양균%왕겸%리조영%초영부%구동천%초저%진발희%격상%색다
棘球绦虫%流行病学%粪抗原%风险因子%控制%流行%中国
棘毬縚蟲%流行病學%糞抗原%風險因子%控製%流行%中國
극구조충%류행병학%분항원%풍험인자%공제%류행%중국
Echinococcus%Epidemiology%Ooproantigen%Risk factor%Control%Prevalence%China
目的 对四川省甘孜县达通玛藏族牧区家犬感染细粒棘球棘球绦虫和多房棘球棘球绦虫进行流行病学调查和评价感染风险因素.方法 分别对甘孜县达通玛藏族牧区查龙、卡龙、大德和查扎等4乡的犬主进行问卷调查,了解家犬感染棘球绦虫的相关因素.剖检流浪犬,检测棘球绦虫感染率,并用此结果 评价粪抗原-ELISA方法 .用该方法 检测家犬感染棘球绦虫的阳性率,评价犬驱虫效果.用X2检验和方差分析对结果 进行统计. 结果 2000年流浪犬棘球绦虫感染率为60.9%(14/23),其中细粒棘球绦虫感染率为26.1%(6/23),多房棘球绦虫感染率为34.8%(8/23).粪抗原-EUSA特异性为80.0%,敏感性为9213%.家犬粪抗原-EUSA阳性率平均为50%(290/580).从2003年起,经每半年1次吡喹酮犬驱虫(5 mg/kg),2005年同一犬群粪抗原阳性率降为17.0%(99/580).犬感染风险因素调查发现敞放犬粪抗原阳性率[40.4%(65/161)]明显高于半栓养犬[白天拴养夜晚放养的犬32.3%(109,337);夜晚拴养白天放养的犬29.2%(21/72)]及一直栓养的犬[20%(2/10)1(P＜0.01);主人缺乏防治相关知识的犬[38.1%(121/318)]和不进行驱虫的犬[47.7%(92/193)],阳性率明显高于主人具有相关知识[28.6%(75/262)]和驱虫犬120.4%(79/387)](P＜0.05和P＜0.01).粪抗原-ELISA阳性率与犬的年龄、性别和饲养家畜的种类无关.结论 四川省甘孜县达通玛藏族牧区是家犬两种棘球绦虫病流行区.粪抗原-EUSA法可用于检测犬棘球蚴病.犬敞放和不对犬驱虫,以及牧民缺乏相关知识是造成家犬棘球蚴病传播、流行的重要原因.
目的 對四川省甘孜縣達通瑪藏族牧區傢犬感染細粒棘毬棘毬縚蟲和多房棘毬棘毬縚蟲進行流行病學調查和評價感染風險因素.方法 分彆對甘孜縣達通瑪藏族牧區查龍、卡龍、大德和查扎等4鄉的犬主進行問捲調查,瞭解傢犬感染棘毬縚蟲的相關因素.剖檢流浪犬,檢測棘毬縚蟲感染率,併用此結果 評價糞抗原-ELISA方法 .用該方法 檢測傢犬感染棘毬縚蟲的暘性率,評價犬驅蟲效果.用X2檢驗和方差分析對結果 進行統計. 結果 2000年流浪犬棘毬縚蟲感染率為60.9%(14/23),其中細粒棘毬縚蟲感染率為26.1%(6/23),多房棘毬縚蟲感染率為34.8%(8/23).糞抗原-EUSA特異性為80.0%,敏感性為9213%.傢犬糞抗原-EUSA暘性率平均為50%(290/580).從2003年起,經每半年1次吡喹酮犬驅蟲(5 mg/kg),2005年同一犬群糞抗原暘性率降為17.0%(99/580).犬感染風險因素調查髮現敞放犬糞抗原暘性率[40.4%(65/161)]明顯高于半栓養犬[白天拴養夜晚放養的犬32.3%(109,337);夜晚拴養白天放養的犬29.2%(21/72)]及一直栓養的犬[20%(2/10)1(P＜0.01);主人缺乏防治相關知識的犬[38.1%(121/318)]和不進行驅蟲的犬[47.7%(92/193)],暘性率明顯高于主人具有相關知識[28.6%(75/262)]和驅蟲犬120.4%(79/387)](P＜0.05和P＜0.01).糞抗原-ELISA暘性率與犬的年齡、性彆和飼養傢畜的種類無關.結論 四川省甘孜縣達通瑪藏族牧區是傢犬兩種棘毬縚蟲病流行區.糞抗原-EUSA法可用于檢測犬棘毬蚴病.犬敞放和不對犬驅蟲,以及牧民缺乏相關知識是造成傢犬棘毬蚴病傳播、流行的重要原因.
목적 대사천성감자현체통마장족목구가견감염세립극구극구조충화다방극구극구조충진행류행병학조사화평개감염풍험인소.방법 분별대감자현체통마장족목구사룡、잡룡、대덕화사찰등4향적견주진행문권조사,료해가견감염극구조충적상관인소.부검류랑견,검측극구조충감염솔,병용차결과 평개분항원-ELISA방법 .용해방법 검측가견감염극구조충적양성솔,평개견구충효과.용X2검험화방차분석대결과 진행통계. 결과 2000년류랑견극구조충감염솔위60.9%(14/23),기중세립극구조충감염솔위26.1%(6/23),다방극구조충감염솔위34.8%(8/23).분항원-EUSA특이성위80.0%,민감성위9213%.가견분항원-EUSA양성솔평균위50%(290/580).종2003년기,경매반년1차필규동견구충(5 mg/kg),2005년동일견군분항원양성솔강위17.0%(99/580).견감염풍험인소조사발현창방견분항원양성솔[40.4%(65/161)]명현고우반전양견[백천전양야만방양적견32.3%(109,337);야만전양백천방양적견29.2%(21/72)]급일직전양적견[20%(2/10)1(P＜0.01);주인결핍방치상관지식적견[38.1%(121/318)]화불진행구충적견[47.7%(92/193)],양성솔명현고우주인구유상관지식[28.6%(75/262)]화구충견120.4%(79/387)](P＜0.05화P＜0.01).분항원-ELISA양성솔여견적년령、성별화사양가축적충류무관.결론 사천성감자현체통마장족목구시가견량충극구조충병류행구.분항원-EUSA법가용우검측견극구유병.견창방화불대견구충,이급목민결핍상관지식시조성가견극구유병전파、류행적중요원인.
Objective To determine the prevalence and evaluate the risk factors of canine echinococcosis based on a field survey of dog infections with Echinococcus granulosus and E muhilocularis in Chalong，Kalong，Dade and Chazha Townships in a district of Ganzi County，Sichuan Province，China.Method Questionnairing associated with the acquisition of canine echinococcosis was administered to dog owners.Stray dogs were examined post-mortem and rectal faeces at necropsy were collected to validate a coproantigen EHSA.Owned dogs were screened for Echinococcus spp.infection in faeces using the genus specific copro-ELISA and the effectiveness of dog treatment was assessed.Chisquare and one-way ANOVA were used for statistical analysis.Results The prevalence of Echinococcus spp.infection at necropsy in stray dogs was 60.9% (14/23) in 2000；E.muultilocularis infection accounted for 34.8% (8/23) and E.granulosus for 26.1%(6/23).The specificity of the copro-ELISA was 80.0%and the sensitivity waft 92.3%，compared with the results at necropsy.Fifty percent of owned dogs(290/580)tested was coproantigen positive at the beginning of the project in 2000，which decreased to 17%(99/580)in the sanle cohort of owned dogs after praziquantel treatment(5 mg/kg)at 6-monthly period from 2003 to 2005.Analysis for risk factors associated with coproantigen positive dogs showed that the never tethered dogs had a higher rate(40.4%，65/161)than dogs tethered during the day(32.3%，109/337)，or tethered at night[29.2%(21/72].or those always tethered[20%(2/10)](P＜0.01).Dogs that their owners lacked hydatid transmission knowledge[38.1%(121/318)]and did not have de-worming practice[47.7%(92/193)] had significantly higher copro-antigen positive rate than those dogs that their owners knew relevant knowledge[28.6%(75/262)]and were dewormed reSuhay[20.4%(79/387)](P＜0.05 and P＜0.01).There was no correlation between the prevalence and dog sex or age or the vaileties of livestock that the owner raised.Conclusion Local dogs show high prevalence with beth E.granulosus and E.multilocularis.The copro-ELISA can be used to detect infection of Echinococcus in dogs.Allowing dogs to roam，lack of the basic knowledge of hydatid disease transmission and no de-worming practice for dogs are significant factors for the transmission of canine echinococcosis.
