实用临床医学
實用臨床醫學
실용림상의학
Practical Clinical Medicine
2009年
5期
41-42,47
,共3页
2型糖尿病%胰岛素泵%感染
2型糖尿病%胰島素泵%感染
2형당뇨병%이도소빙%감염
type 2 diabetes%insulin pump%infection
目的 观察胰岛素泵持续皮下注射胰岛素治疗2型糖尿病高血糖状态合并感染的临床效果及安全性,并与常规皮下注射胰岛素进行比较.方法 将52例2型糖尿病高血糖合并感染患者随机分为治疗组与对照组,治疗组采用胰岛素泵,对照组采用皮下注射胰岛素,比较2组患者的空腹血糖、餐后2 h血糖、血糖达稳态的时间、所需胰岛素剂量、感染控制时间、患者平均住院天数及低血糖发生率等.结果 治疗组与对照组感染控制时间分别为(7.1±2.2)d和(9.5±3.0)d(P<0.01),达标血糖时间分别为(4.6±0.8)d和(7.1±2.6)d(P<0.01),低血糖发生次数分别为(0.5±0.7)次/人和(1.0±1.1)次/人(P<0.05).2组患者治疗后空腹和餐后2 h血糖均明显下降(P<0.01),治疗组下降明显高于对照组(P<0.05).结论 采用胰岛素泵持续皮下注射胰岛素治疗2型糖尿病高血糖合并感染患者疗效可靠,控制血糖快速平稳,胰岛素泵是糖尿病高血糖合并感染急性期的一种理想的胰岛素输注模式.
目的 觀察胰島素泵持續皮下註射胰島素治療2型糖尿病高血糖狀態閤併感染的臨床效果及安全性,併與常規皮下註射胰島素進行比較.方法 將52例2型糖尿病高血糖閤併感染患者隨機分為治療組與對照組,治療組採用胰島素泵,對照組採用皮下註射胰島素,比較2組患者的空腹血糖、餐後2 h血糖、血糖達穩態的時間、所需胰島素劑量、感染控製時間、患者平均住院天數及低血糖髮生率等.結果 治療組與對照組感染控製時間分彆為(7.1±2.2)d和(9.5±3.0)d(P<0.01),達標血糖時間分彆為(4.6±0.8)d和(7.1±2.6)d(P<0.01),低血糖髮生次數分彆為(0.5±0.7)次/人和(1.0±1.1)次/人(P<0.05).2組患者治療後空腹和餐後2 h血糖均明顯下降(P<0.01),治療組下降明顯高于對照組(P<0.05).結論 採用胰島素泵持續皮下註射胰島素治療2型糖尿病高血糖閤併感染患者療效可靠,控製血糖快速平穩,胰島素泵是糖尿病高血糖閤併感染急性期的一種理想的胰島素輸註模式.
목적 관찰이도소빙지속피하주사이도소치료2형당뇨병고혈당상태합병감염적림상효과급안전성,병여상규피하주사이도소진행비교.방법 장52례2형당뇨병고혈당합병감염환자수궤분위치료조여대조조,치료조채용이도소빙,대조조채용피하주사이도소,비교2조환자적공복혈당、찬후2 h혈당、혈당체은태적시간、소수이도소제량、감염공제시간、환자평균주원천수급저혈당발생솔등.결과 치료조여대조조감염공제시간분별위(7.1±2.2)d화(9.5±3.0)d(P<0.01),체표혈당시간분별위(4.6±0.8)d화(7.1±2.6)d(P<0.01),저혈당발생차수분별위(0.5±0.7)차/인화(1.0±1.1)차/인(P<0.05).2조환자치료후공복화찬후2 h혈당균명현하강(P<0.01),치료조하강명현고우대조조(P<0.05).결론 채용이도소빙지속피하주사이도소치료2형당뇨병고혈당합병감염환자료효가고,공제혈당쾌속평은,이도소빙시당뇨병고혈당합병감염급성기적일충이상적이도소수주모식.
Objective To compare the therapeutic effects and safety of continuous subcutaneous insulin infusion by insulin pump and multiple subcutaneous insulin injection in treatment of hyperglycemia of type 2 diabetes accompanied with infection.Methods A total of 52 patients with T2DM accompanied with infection were divided into 2 groups,one group treated by continuous subcutaneous insulin infusion(treatment group),and the other by multiple daily insulin injection(control group).Blood glucose levels days needed for achieving good control,insulin doses and hypoglycemic episodes were compared in the two groups.Result It took (7.1±2.2)d in treatment group and (9.5±3.0)d in control group to control infection(P＜0.01).The time for well controlled blood glucose levels in 2 groups were (4.6±0.8)d and (7.1±2.6)d respectively(P＜0.01).The frequency of hypoglycemic of 2 groups were (0.5±0.7) and (1.0±1.1)per person respectively(P＜0.05).The level of blood gluome control were both remarkably induced after using two diferent ways of insulin delivery.There was significantly difference in two groups(P<0.05).Conclusion Insulin pump could achieve faster and better serum glucose control with a lower dose than convention therapy in the treatment of hyperglycemia of T2DM patients accompanied with acute infections.
