CAJ | 학술논문

目的了解类风湿关节炎(RA)合并抑郁状态的发生率,并对其相关因素进行探讨.方法对159例RA患者采用抑郁自评量表、汉密尔顿抑郁量表等进行评分,得到本组患者抑郁状态的发生率,并对抑郁和非抑郁的RA患者进行对比分析,其中正态分布计量资料的比较采用t检验,计数资料采用X2检验,与抑郁发病风险相关的危险因素用Logistic回归分析.结果 RA合并抑郁的发生率为39.6％(63/159),发生的相关因素为健康评估问卷残疾指数(HAQ-DI)(OR=3.276,95％CI 1.315～7.814,P=0.003)、关节压痛数(OR =2.252,95％CI 1.117～3.362,P=0.029)、低收入家庭(OR=1.629,95％CI 1.215～2.437,P=0.031)、C反应蛋白(CRP)(OR=1.528,95％CI 1.112～2.294,P=0.040).结论抑郁状态在RA患者中常见,高HAQ-DI积分、CRP,低收入家庭和较多的关节压痛数的RA患者更容易合并抑郁.
목적 료해류풍습관절염(RA)합병억욱상태적발생솔,병대기상관인소진행탐토.방법 대159례RA환자채용억욱자평량표、한밀이돈억욱량표등진행평분,득도본조환자억욱상태적발생솔,병대억욱화비억욱적RA환자진행대비분석,기중정태분포계량자료적비교채용t검험,계수자료채용X2검험,여억욱발병풍험상관적위험인소용Logistic회귀분석.결과 RA합병억욱적발생솔위39.6％(63/159),발생적상관인소위건강평고문권잔질지수(HAQ-DI)(OR=3.276,95％CI 1.315～7.814,P=0.003)、관절압통수(OR =2.252,95％CI 1.117～3.362,P=0.029)、저수입가정(OR=1.629,95％CI 1.215～2.437,P=0.031)、C반응단백(CRP)(OR=1.528,95％CI 1.112～2.294,P=0.040).결론 억욱상태재RA환자중상견,고HAQ-DI적분、CRP,저수입가정화교다적관절압통수적RA환자경용역합병억욱.
Objective To survey the incidence of depression in rheumatoid arthritis (RA) and explore the related factors.Methods One hundred and fifty-nine patients with RA were investigated.All of them were assessed by depression scale and Hamilton Depression Rating Scale.A mono-variate and multivariate Logistic regression analysis were carried out to determine the factors that best related to the occurrence of depression in RA.Results The overall incidence rate was 39.6％.The regression analysis showed that factors related to the occurrence of depression in RA were HAQ-DI (OR=3.276,95％CI 1.315-7.814,P=0.003),the number of tender joints (OR=2.252,95％CI 1.117-3.362,P=0.029),low-income families (OR=1.629,95％CI 1.215-2.437,P=0.031 ) and serum CRP level (OR=1.528,95％CI 1.112-2.294,P=0.040).Conclusion Depression is common in patients with RA.Patients who have high HAQ-DI,CRP and from low-income families with more tender joints tend to develop depression.