CAJ | 학술논문

目的探讨伽玛刀对小儿血管网状细胞瘤术后残留的治疗作用. 方法回顾性分析9例小儿血管网状细胞瘤术后残留行伽玛刀治疗的临床资料,其中等剂量曲线范围平均50%,周边剂量平均18 Gy,肿瘤中心剂量平均36.5 Gy. 结果 9例患儿随访时间12～48个月,6例患儿肿瘤缩小50%以上,临床症状和体征得到明显改善;1例患儿无变化并再次行伽玛刀治疗;2例患儿肿瘤进行性增大,其中1例第二次伽玛刀治疗,1例第二次行开颅手术治疗. 结论伽玛刀对小儿血管网状细胞瘤术后残留的治疗是一种安全、有效的方法 .但要严格掌握适应证.
목적 탐토가마도대소인혈관망상세포류술후잔류적치료작용. 방법 회고성분석9례소인혈관망상세포류술후잔류행가마도치료적림상자료,기중등제량곡선범위평균50%,주변제량평균18 Gy,종류중심제량평균36.5 Gy. 결과 9례환인수방시간12～48개월,6례환인종류축소50%이상,림상증상화체정득도명현개선;1례환인무변화병재차행가마도치료;2례환인종류진행성증대,기중1례제이차가마도치료,1례제이차행개로수술치료. 결론 가마도대소인혈관망상세포류술후잔류적치료시일충안전、유효적방법 .단요엄격장악괄응증.
Objective To assess the therapeutic effect of gamma knife radiosurgery for residual tumors after surgical resection of hemangioblastoma in children. Methods The clinical data were retrospectively analyzed in 9 children who received gamma knife radiosurgery for the residual tumors after a previous surgery for hemangioblastoma resection. Results The 9 children were followed up for 12-48 months, and 6 children showed a tumor volume reduction by over 50% with obviously improved clinical symptoms. One child showed no response to the treatment and received a second gamma knife radiosurgery. In 2 children, the tumor volume increased progressively after the radiosurgery, and a second radiosurgery was performed in 1 case and open surgery in the other. Conclusion Gamma knife radiosurgery is safe and effective for treatment of the residual tumors in children with previous surgical resection of hemangioblastoma.