CAJ | 학술논문

大多数疾病均伴随着炎症的发生,炎症反应加重疾病的发生和症状.炎症介质主要由花生四烯酸代谢产生,不同的花生四烯酸代谢通路的产物有着不同的生理活性,在炎症中发挥着重要作用.了解花生四烯酸代谢的3条通路中的关键产物(如PGE2、LTXs和EETs等)在炎症反应中的作用及通路之间的相互影响具有重要意义.
대다수질병균반수착염증적발생,염증반응가중질병적발생화증상.염증개질주요유화생사희산대사산생,불동적화생사희산대사통로적산물유착불동적생리활성,재염증중발휘착중요작용.료해화생사희산대사적3조통로중적관건산물(여PGE2、LTXs화EETs등)재염증반응중적작용급통로지간적상호영향구유중요의의.
Inflammation occurs in various diseases.It can deteriorate the process of disease and cause with serious output.The main sources of inflammation mediators are the products of arachidonic acid metabolism.Various products of play ara chidonic acid metabolism different roles during inflammation.The review focuses on the recent update about three key metabolic products of arachidonic acid metabolism(such as PGE2、LTXs and EETs)and their contribution in inflammation initiation,and the interaction of these three pathways.