CAJ | 학술논문

云南省地方性不明原因猝死危险因素的病例对照研究
운남성지방성불명원인졸사위험인소적병례대조연구
A case-control study on the risk factors of Yunnan endemic sudden cardiac death

万方数据

中国地方病学杂志中國地方病學雜誌 중국지방병학잡지
CHINESE JOURNAL OF ENDEMIOLOGY
2008年 4期 419-421 ,共3页

蒋长兴%李兴洲%裴俊瑞%高琳%李奇%冯红旗%夏德义%邓晶%王宇%刘明法%李少臣%王铜

장장흥%리흥주%배준서%고림%리기%풍홍기%하덕의%산정%왕우%류명법%리소신%왕동

猝死%危险因素%病例对照研究猝死%危險因素%病例對照研究
졸사%위험인소%병례대조연구
Death,sudden%Risk factors%Case-control studies

目的探讨可能引起云南省地方性不明原因猝死的危险因素,为制订确实有效的预防措施提供依据.方法在猝死病区选择病例22人,在非病区选择对照24人,对病例和对照采用统一的调查表进行现场询问,应用SPSS 13.0统计软件进行单因素X2检验及多冈素lobistic回归筛选可疑危险因素,建立并评价最优回归模型.结果经单因素X2检验,发现餐具存放位置、家中有无牲畜圈、发病前是否食用蕈子、发病前是否接触农药杀虫剂、发病前是否气候骤变5个可疑因素具有统计学意义(X2值分别为12.206、4.779、5.741、6.120、10.754,P<0.05);经多因素logistic回归筛选出食用蕈子为保护性因素[比值比(OR)=0.115,P<0.05)],气候骤变为危险因素(OR=36.592,P<0.01).结论气候骤变可能是云南省地方性不明原因猝死的发病诱因,在猝死高发季节到来前食用蕈子可以起到一定的预防作用.
목적 탐토가능인기운남성지방성불명원인졸사적위험인소,위제정학실유효적예방조시제공의거.방법 재졸사병구선택병례22인,재비병구선택대조24인,대병례화대조채용통일적조사표진행현장순문,응용SPSS 13.0통계연건진행단인소X2검험급다강소lobistic회귀사선가의위험인소,건립병평개최우회귀모형.결과 경단인소X2검험,발현찬구존방위치、가중유무생축권、발병전시부식용심자、발병전시부접촉농약살충제、발병전시부기후취변5개가의인소구유통계학의의(X2치분별위12.206、4.779、5.741、6.120、10.754,P<0.05);경다인소logistic회귀사선출식용심자위보호성인소[비치비(OR)=0.115,P<0.05)],기후취변위위험인소(OR=36.592,P<0.01).결론 기후취변가능시운남성지방성불명원인졸사적발병유인,재졸사고발계절도래전식용심자가이기도일정적예방작용.
Objective To explore the potential risk factors to Ymman endemic sudden cardiac death (YESCD) and provide evidence for prevention. Methods Twenty-two cases and 24 controls were randomly selected from YESCD areas and non-YESCD areas, respectively. Both cases and controls were interviewed with unified questionnaires. Univatiate X2 test and multivariate conditional logistic stepwise regression was conducted with SPSS 13.0. The optimal regression model was established and evaluated. Results The univariate X2 teat revealed that presence or absence of 5 potential factors might possibly be associated to YESCD: appropriate places for storing dining utensils, pens for livestock, consumption of mushrooms, exposure to any pesticides, and sudden climate changes before onset(X2=12.206,4.779,5.741,6.120,10.754, P<0.05). Multivariate conditional logistic stepwise regression demonstrated that consumption of mushrooms was a protective factor(OR=0.115, P<0.05) and sudden climate change was a risk factor(OR=36.592, P<0.01). Conclusions Sudden climate change might be a risk factor contributing to YESCD, and eating mushrooms before the prevalence seasons may provide some protection.