CAJ | 학술논문

目的为骺板组织工程寻找生物相容性良好的支架材料.方法将体外培养的第三代骺板软骨细胞与可降解多孔丝素材料复合.应用扫描电镜、激光共聚焦显微镜、MTT等方法,对骺板软骨细胞与可降解多孔丝素材料的生物相容性进行观察.结果骺板软骨细胞在可降解多孔丝素材料上生长良好,随着培养时间的延长,骺板软骨细胞逐渐增多.结论可降解多孔丝素材料具有良好的生物相容性,可以作为骺板组织工程理想的支架材料.
목적 위후판조직공정심조생물상용성량호적지가재료.방법 장체외배양적제삼대후판연골세포여가강해다공사소재료복합.응용소묘전경、격광공취초현미경、MTT등방법,대후판연골세포여가강해다공사소재료적생물상용성진행관찰.결과 후판연골세포재가강해다공사소재료상생장량호,수착배양시간적연장,후판연골세포축점증다.결론 가강해다공사소재료구유량호적생물상용성,가이작위후판조직공정이상적지가재료.
Objective To assessfind the biocompatibility of scaffold SF for epiphyseal plate tissue engineering. Methods To culture the epiphyseal plate chondrocyte on scaffold SF. We studied biological characteristics of the cells by applying the ways of scanning electron- microscope, laser scan confocal microscope and MTT test. Results The epiphyseal plate chondrocyte grew well on scaffold SF. Conclusions The scaffold SF have good biocompatibility and can be used as ideal scaffold in epiphyseal plate tissue engineering.