中华全科医师杂志
中華全科醫師雜誌
중화전과의사잡지
CHINESE JOURNAL OF GENERAL PRACTITIONERS
2008年
4期
239-242
,共4页
蒋秋明%高燕明%卢桂芝%周军%谢玲玎%张惠敏%董松%彭春霞%郭晓蕙%高妍
蔣鞦明%高燕明%盧桂芝%週軍%謝玲玎%張惠敏%董鬆%彭春霞%郭曉蕙%高妍
장추명%고연명%로계지%주군%사령정%장혜민%동송%팽춘하%곽효혜%고연
甲状腺疾病%发病率%横断面研究%问卷调查
甲狀腺疾病%髮病率%橫斷麵研究%問捲調查
갑상선질병%발병솔%횡단면연구%문권조사
Thyroid diseases%Incidence%Cross-sectional studies%Questionnaire
目的 了解北京城区成年人群亚临床甲状腺功能异常的发病情况.方法 2002年共1966人进行体检并测定血清促甲状腺激素(TSH)、甲状腺激素(T3、T4)及抗甲状腺过氧化物酶抗体(TPOAb).2004年随访到1646人,随访率83.72%.结果 亚临床甲状腺功能减退症(亚甲减)及亚临床甲状腺功能亢进症(亚甲亢)的年发病率分别为1.72%和0.25%.女性＞40岁组亚甲减年发病率高于≤40岁组,差异有统计学意义(χ2=10.869,P＜0.01),而男性两年龄组比较差异无统计学意义.＞40岁组亚甲减年发病率女性高于男性(χ2=24.122,P＜0.01),而≤40岁组男女发病率比较差异无统计学意义.亚甲亢两年龄组男女比较差异均无统计学意义.亚甲减既往史阳性组年发病率高于阴性组(χ2=6.898,P＜0.01);家族史比较差异无统计学意义.亚甲亢既往史、家族史比较均无统计学意义.TPOAb阳性组亚甲减年发病率高于阴性组(χ2=14.084,P＜0.01);而亚甲亢年发病率比较,差异无统计学意义.结论 北京城区部分体检人群亚甲减发病率偏高,高龄、女性和TPOAb阳性者发病倾向更高.
目的 瞭解北京城區成年人群亞臨床甲狀腺功能異常的髮病情況.方法 2002年共1966人進行體檢併測定血清促甲狀腺激素(TSH)、甲狀腺激素(T3、T4)及抗甲狀腺過氧化物酶抗體(TPOAb).2004年隨訪到1646人,隨訪率83.72%.結果 亞臨床甲狀腺功能減退癥(亞甲減)及亞臨床甲狀腺功能亢進癥(亞甲亢)的年髮病率分彆為1.72%和0.25%.女性＞40歲組亞甲減年髮病率高于≤40歲組,差異有統計學意義(χ2=10.869,P＜0.01),而男性兩年齡組比較差異無統計學意義.＞40歲組亞甲減年髮病率女性高于男性(χ2=24.122,P＜0.01),而≤40歲組男女髮病率比較差異無統計學意義.亞甲亢兩年齡組男女比較差異均無統計學意義.亞甲減既往史暘性組年髮病率高于陰性組(χ2=6.898,P＜0.01);傢族史比較差異無統計學意義.亞甲亢既往史、傢族史比較均無統計學意義.TPOAb暘性組亞甲減年髮病率高于陰性組(χ2=14.084,P＜0.01);而亞甲亢年髮病率比較,差異無統計學意義.結論 北京城區部分體檢人群亞甲減髮病率偏高,高齡、女性和TPOAb暘性者髮病傾嚮更高.
목적 료해북경성구성년인군아림상갑상선공능이상적발병정황.방법 2002년공1966인진행체검병측정혈청촉갑상선격소(TSH)、갑상선격소(T3、T4)급항갑상선과양화물매항체(TPOAb).2004년수방도1646인,수방솔83.72%.결과 아림상갑상선공능감퇴증(아갑감)급아림상갑상선공능항진증(아갑항)적년발병솔분별위1.72%화0.25%.녀성＞40세조아갑감년발병솔고우≤40세조,차이유통계학의의(χ2=10.869,P＜0.01),이남성량년령조비교차이무통계학의의.＞40세조아갑감년발병솔녀성고우남성(χ2=24.122,P＜0.01),이≤40세조남녀발병솔비교차이무통계학의의.아갑항량년령조남녀비교차이균무통계학의의.아갑감기왕사양성조년발병솔고우음성조(χ2=6.898,P＜0.01);가족사비교차이무통계학의의.아갑항기왕사、가족사비교균무통계학의의.TPOAb양성조아갑감년발병솔고우음성조(χ2=14.084,P＜0.01);이아갑항년발병솔비교,차이무통계학의의.결론 북경성구부분체검인군아갑감발병솔편고,고령、녀성화TPOAb양성자발병경향경고.
Objective To understand the incidence of subclinical thyroid dysfunction in adult population of Beijing.Methods Serum levels of thyroid-stimulating hormone(TSH),T3,T4 and thyroid peroxidase antibody(TPOAb)were measured for 1966 persons living in Beijing by physical examinations in 2002,and 1646 of them(83.72%)were followed-up in 2004.Results Overall incidence of subclinical hypothyroidism and subclinical hyperthyroidism were 1.72 percent and 0.25 percent,respectively.Incidence of subclinical hypothyroidism in females aged ＞40 years was significantly higher than that in those ≤40 years(χ2=10.869,P＜0.01),but no significant difference between those ＞40 and ≤40 years in males was found.Incidence of subclinical hypothyroidism in females was significantly higher than that in males ＞40 years of age(χ2=24.122,P＜0.01),but no significant difference between females and males ≤40 years was found.No significant difference in incidence of subclinical hypothyroidism was noticed between varied age groups and between males and females.Incidence of subclinical hypothyroidism was significantly higher in those with history of subclinical hypothyroidism than that in those without it(χ2= 6.898,P＜0.01).No significant difference in incidence of subclinical hypothyroidism between those with family history of thyroid disease and those without it was found.Incidence of subclinical hypothyroidism was significantly higher in those with positive TPOAb than that in those with negative one(χ2=14.084,P＜0.01),but no significant difference in incidence of subclinical hyperthyroidism between those with positive and negative TPOAb was found.Conclusion Incidence of subclinical hypothyroidism was a little bit higher in population of Beijing area by physical examinations,particularly in females,elder age and positive TPOAb.
