CAJ | 학술논문

目的评价血清CA125在附件包块中的鉴别诊断价值.方法对2006年1月至2008年12月中山大学附属第三医院妇科收治的375例附件包块进行回顾性分析.结果 375例附件包块中,血清CA125＞35 U/ml的有198例,其中卵巢恶性肿瘤92例,附件良性包块106例,分别占46.5%和53.5%,但卵巢恶性肿瘤的血清CA125值高于附件良性包块(P＜0.05),而且CA125取值不断升高时,附件包块的患者中诊断为卵巢恶性肿瘤的比例就越来越高.当血清CA125＞65 U/ml时,检出卵巢恶性肿瘤的敏感性、特异性和诊断准确性都较高,分别为84.5%、80.1%和81.3%.当血清CA125＞150 U/ml时,提示晚期卵巢恶性肿瘤的敏感性、特异性和诊断准确性都较好,分别为84.4%、76.3%和78.4%.结论血清CA125取65 U/ml是临床鉴别诊断附件良恶性肿瘤的较佳临界值;当血清CA125＞150 U/ml时,提示晚期卵巢恶性肿瘤的意义较大.
목적 평개혈청CA125재부건포괴중적감별진단개치.방법 대2006년1월지2008년12월중산대학부속제삼의원부과수치적375례부건포괴진행회고성분석.결과 375례부건포괴중,혈청CA125＞35 U/ml적유198례,기중란소악성종류92례,부건량성포괴106례,분별점46.5%화53.5%,단란소악성종류적혈청CA125치고우부건량성포괴(P＜0.05),이차CA125취치불단승고시,부건포괴적환자중진단위란소악성종류적비례취월래월고.당혈청CA125＞65 U/ml시,검출란소악성종류적민감성、특이성화진단준학성도교고,분별위84.5%、80.1%화81.3%.당혈청CA125＞150 U/ml시,제시만기란소악성종류적민감성、특이성화진단준학성도교호,분별위84.4%、76.3%화78.4%.결론 혈청CA125취65 U/ml시림상감별진단부건량악성종류적교가림계치;당혈청CA125＞150 U/ml시,제시만기란소악성종류적의의교대.
Objective To Study of the value of serum CA125 in differential diagnosis for adnexal mass.Methods Retrospective analysis was utilized to analyze the clinical materials of 375 eases of adnexal mass in the 3th Affiliated Hospital of SUN Yat-sen University from January 2006 to December 2008.Results 198 cases,serum CA125 were＞35 U/ml,including 92 cases of malignant ovarian tumor and 106 cases of benigh adnexal mass,but CA125 value of malignant ovarian tumor was higher significantly than that of benigh adnexal mass (P＜0.05).When serum CA125 was＞65 U/ml,the sensitivity,specificity and accuracy were better for diagnosis of malignant ovarian tumor,which were 84.5%,80.1% and 81.3% respectively.When serum CA125 was＞150 U/ml,the sensitivity,specificity and accuracy were better for the diagnosis of advanced malignant ovarian tumor,which were 84.4%,76.3% and 78.4% respectively.Conclusion 65 U/ml of serious CA125 was the more suitable cut-off for differential diagnosis of malignant or benigh adnexal mass,and 150 U/ml for advanced or early stage of malignant ovarian tumor.