中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2012年
6期
445-448
,共4页
宋笑凯%王文静%李淮玉%任明山%吴蕾%马俊芳
宋笑凱%王文靜%李淮玉%任明山%吳蕾%馬俊芳
송소개%왕문정%리회옥%임명산%오뢰%마준방
短暂性脑缺血发作%脑梗死%ABCD3-Ⅰ评分
短暫性腦缺血髮作%腦梗死%ABCD3-Ⅰ評分
단잠성뇌결혈발작%뇌경사%ABCD3-Ⅰ평분
Transient ischaemic attack%Cerebral infarction%ABCD3-I criteria
目的 探讨应用ABCD3-Ⅰ评分评估短暂性脑缺血发作(TIA)患者早期卒中风险.方法 分别采用ABCD2、ABCD3与ABCD3-Ⅰ评分标准对107例TIA患者进行评分,并观察患者TIA后2d和7d内脑梗死的发生率.结果ABCD2、ABCD3与ABCD3-Ⅰ评分法预测2d内脑梗死风险的ROC曲线下面积(AUCRoc)分别为0.61、0.66和0.71,预测7d内脑梗死风险的AUCRoc分别为0.62、0.68和0.74.107例TIA患者2d内进展为脑梗死者13例(12.1%),7d内进展为脑梗死者24例(22.4%).其中ABCD3-Ⅰ评分0~3分的低危组患者17例,4~7分的中危组患者54例,8~13分的高危组患者36例,评分值越高TIA后短期内脑梗死发生率越高.除年龄因素外,ABCD3-Ⅰ评分法中各个评分项目对TIA后2d和7d内脑梗死发生率均有明显影响(P<0.05).结论 ABCD3-Ⅰ评分法可更好地预测TIA后早期缺血性卒中风险,可作为常规应用于临床,指导TIA危险分层评价和治疗.
目的 探討應用ABCD3-Ⅰ評分評估短暫性腦缺血髮作(TIA)患者早期卒中風險.方法 分彆採用ABCD2、ABCD3與ABCD3-Ⅰ評分標準對107例TIA患者進行評分,併觀察患者TIA後2d和7d內腦梗死的髮生率.結果ABCD2、ABCD3與ABCD3-Ⅰ評分法預測2d內腦梗死風險的ROC麯線下麵積(AUCRoc)分彆為0.61、0.66和0.71,預測7d內腦梗死風險的AUCRoc分彆為0.62、0.68和0.74.107例TIA患者2d內進展為腦梗死者13例(12.1%),7d內進展為腦梗死者24例(22.4%).其中ABCD3-Ⅰ評分0~3分的低危組患者17例,4~7分的中危組患者54例,8~13分的高危組患者36例,評分值越高TIA後短期內腦梗死髮生率越高.除年齡因素外,ABCD3-Ⅰ評分法中各箇評分項目對TIA後2d和7d內腦梗死髮生率均有明顯影響(P<0.05).結論 ABCD3-Ⅰ評分法可更好地預測TIA後早期缺血性卒中風險,可作為常規應用于臨床,指導TIA危險分層評價和治療.
목적 탐토응용ABCD3-Ⅰ평분평고단잠성뇌결혈발작(TIA)환자조기졸중풍험.방법 분별채용ABCD2、ABCD3여ABCD3-Ⅰ평분표준대107례TIA환자진행평분,병관찰환자TIA후2d화7d내뇌경사적발생솔.결과ABCD2、ABCD3여ABCD3-Ⅰ평분법예측2d내뇌경사풍험적ROC곡선하면적(AUCRoc)분별위0.61、0.66화0.71,예측7d내뇌경사풍험적AUCRoc분별위0.62、0.68화0.74.107례TIA환자2d내진전위뇌경사자13례(12.1%),7d내진전위뇌경사자24례(22.4%).기중ABCD3-Ⅰ평분0~3분적저위조환자17례,4~7분적중위조환자54례,8~13분적고위조환자36례,평분치월고TIA후단기내뇌경사발생솔월고.제년령인소외,ABCD3-Ⅰ평분법중각개평분항목대TIA후2d화7d내뇌경사발생솔균유명현영향(P<0.05).결론 ABCD3-Ⅰ평분법가경호지예측TIA후조기결혈성졸중풍험,가작위상규응용우림상,지도TIA위험분층평개화치료.
Objective To assess the ability of ABCD3-Ⅰ score in evaluating the early risk of cerebral infarction after transient ischemic attack ( TIA ).Methods A total of 107 TIA patients were evaluated according to ABCD2,ABCD3 and ABCD3-Ⅰ criteria.The occurrences of cerebral infarction within 2 days and 7 days were observed.Results The AUCRoc of ABCD2,ABCD3 and ABCD3-Ⅰ were 0.61,0.66 and 0.71 in predicting the risk of cerebral infarction within 2 days,and were 0.62,0.68 and 0.74 in predicting within 7 days,respectively.Among 107 patients with TIA,13 evolved into cerebral infarction within 2 days,accounting for 12.1%,and 24 within 7 days,accounting for 22.4%.According to ABCD3-Ⅰ criteria,17 patients were of low risk scored 0-3 ; 54 patients were of medium risk scored 4-7 ; and 36 patients were of high risk scored 8-13.The different incidence of cerebral infarction after TIA was related to ABCD3-Ⅰ score:the higher the score was,the higher incidence was.Except for age factor,every score item of ABCD3-Ⅰ display obvious influence to the occurrence of cerebral infarction within 2 days and 7 days after TIA (P < 0.05 ).Conclusion ABCD3-Ⅰ criteria could more effectively predict the occurrence of early risk of cerebral infarction after TIA,which could be used in regular clinical practice for assistance in TIA risk stratification and treatment.