CAJ | 학술논문

目的探讨β2肾上腺素能受体兴奋剂盐酸利托君期待治疗前置胎盘的效果.方法将60例未足月前置胎盘患者随机分为两组,对照组24例采用硫酸镁治疗；观察组36例采用盐酸利托君治疗.观察组先静脉注射盐酸利托君5μg/min,逐渐加量至35μg/min,根据疗效调节药物用量,待阴道流血停止、无宫缩后,继续维持12h,以后改口服,病情反复者可重复用药.结果盐酸利托君组的保胎成功率、显效时间、延长孕周、妊娠期≥36周比例均明显优于硫酸镁组,两组比较差异均有统计学意义(P＜0.05)；两组阴道出血、产后出血情况和国生儿结局比较差异无统计学意义(P＞0.05).结论盐酸利托君与硫酸镁均可有效抑制宫缩,两者效果相当,但前者起效快、控制出血效果好、延长孕周时间长,值得在临床推广应用.
목적 탐토β2신상선소능수체흥강제염산리탁군기대치료전치태반적효과.방법 장60례미족월전치태반환자수궤분위량조,대조조24례채용류산미치료；관찰조36례채용염산리탁군치료.관찰조선정맥주사염산리탁군5μg/min,축점가량지35μg/min,근거료효조절약물용량,대음도류혈정지、무궁축후,계속유지12h,이후개구복,병정반복자가중복용약.결과 염산리탁군조적보태성공솔、현효시간、연장잉주、임신기≥36주비례균명현우우류산미조,량조비교차이균유통계학의의(P＜0.05)；량조음도출혈、산후출혈정황화국생인결국비교차이무통계학의의(P＞0.05).결론 염산리탁군여류산미균가유효억제궁축,량자효과상당,단전자기효쾌、공제출혈효과호、연장잉주시간장,치득재림상추엄응용.
Objective To investigate the clinical efficacy of ritodrine hydrochloride on placenta previa.Methods Sixty patients with placenta previa were randomly divided into two groups,24 patients in control group were treated with magnesium sulfate,and 36 patients in observation group were treated with ritodrine hydrochloride.Patients in observation group were given intravenous injection of ritodrine hydrochloride 5 μg/min at first,then gradually increased the amount to 35 ~g/min,the drug dosage was agjusted based on efficacy.When vaginal bleeding was stopped,with no contraction,continued to maintain 12 hours,then changed to orally taken,drug use was repeated when the illness relapsed.Results Compared with control group,the success rate of miscarriage,reactive time,the prolongation of gestation,pregnancy rate exceeded 36 weeks were higher in ritodrine hydrochloride group,and there were significant differences between the two groups (P ＜ 0.05).There was no significant difference between the two groups in colporrhagia,postpartum hemorrhage or perinatal outcome (P ＞ 0.05 ).Conclusions Ritodrine hydrochloride and magnesium sulfate can inhibit uterine contractions,both quite effective,but the former with fast onset of action,good effect of blood controling,long prolongation of gestation time,worthy of clinical application.