CAJ | 학술논문

目的观察微波消融治疗术(Microwave Coagulation Therapy,MCT)联合肝动脉栓塞化疗术(Transcatheter Arterial Chemoemoembolization,TACE)治疗中晚期肝癌的临床效果.方法 106例中晚期肝癌患者中,78例采用MCT联合TACE治疗为观察组,其中的42例TACE术后1周联合MCT治疗为观察A组,36例术后2周联合MCT治疗为B组;28例单纯采用TACE治疗为对照组.用SPSS13.0软件分析观察组和对照组、观察A组和B组间术后1个月肝癌病灶碘油沉积率和AFP下降率,以及一年生存率的差异.结果 ①术后1个月AFP降幅良好率观察组为71.8%,对照组为42.9%;碘油沉积良好率观察组为75.6%,对照组为46.4%;1年生存率观察组为52.6%,对照组为25.9%,两组相比观察组优于对照组,P＜0.01,均具有统计学意义.②观察组中术后1个月观察:AFP降幅良好率A组为83.3%,B组为58.3%;碘油沉积良好率A组为85.7%,B组为63.9%;1年生存率A组为64.3%,B组为38.9%,A组优于B组,P＜0.05,均有统计学意义.结论 MCT联合TACE治疗中晚期肝癌,疗效优于单独TACE治疗;TACE术后1周内行MCT治疗,能更有效地形成碘油沉积和降低AFP、提高生存率.TACE术后尽早联合MCT对控制肿瘤、提高生存率有较好的效果.
목적 관찰미파소융치료술(Microwave Coagulation Therapy,MCT)연합간동맥전새화료술(Transcatheter Arterial Chemoemoembolization,TACE)치료중만기간암적림상효과.방법 106례중만기간암환자중,78례채용MCT연합TACE치료위관찰조,기중적42례TACE술후1주연합MCT치료위관찰A조,36례술후2주연합MCT치료위B조;28례단순채용TACE치료위대조조.용SPSS13.0연건분석관찰조화대조조、관찰A조화B조간술후1개월간암병조전유침적솔화AFP하강솔,이급일년생존솔적차이.결과 ①술후1개월AFP강폭량호솔관찰조위71.8%,대조조위42.9%;전유침적량호솔관찰조위75.6%,대조조위46.4%;1년생존솔관찰조위52.6%,대조조위25.9%,량조상비관찰조우우대조조,P＜0.01,균구유통계학의의.②관찰조중술후1개월관찰:AFP강폭량호솔A조위83.3%,B조위58.3%;전유침적량호솔A조위85.7%,B조위63.9%;1년생존솔A조위64.3%,B조위38.9%,A조우우B조,P＜0.05,균유통계학의의.결론 MCT연합TACE치료중만기간암,료효우우단독TACE치료;TACE술후1주내행MCT치료,능경유효지형성전유침적화강저AFP、제고생존솔.TACE술후진조연합MCT대공제종류、제고생존솔유교호적효과.