CAJ | 학술논문

目的探讨70岁以上老年结直肠癌患者接受术后化疗生存及临床受益.方法回顾性分析244例接受过术后辅助化疗的结直肠癌患者,按年龄分为＞70岁和≤70岁两组,Kaplan-Meier生存曲线及COX多因素风险模型分析比较两组患者接受化疗后的总生存.结果两组患者五年生存率分别为63％和62％.Kaplan-Meier生存分析及COX多因素风险模型分析比较,两组患者化疗后总生存差异无显著性(P=0.86,P=0.94).结论年龄不是决定结直肠癌患者化疗生存的独立危险因素,＞70岁的结直肠癌老年患者接受化疗能取得与≤70岁患者相当的临床获益.
목적 탐토70세이상노년결직장암환자접수술후화료생존급림상수익.방법 회고성분석244례접수과술후보조화료적결직장암환자,안년령분위＞70세화≤70세량조,Kaplan-Meier생존곡선급COX다인소풍험모형분석비교량조환자접수화료후적총생존.결과 량조환자오년생존솔분별위63％화62％.Kaplan-Meier생존분석급COX다인소풍험모형분석비교,량조환자화료후총생존차이무현저성(P=0.86,P=0.94).결론 년령불시결정결직장암환자화료생존적독립위험인소,＞70세적결직장암노년환자접수화료능취득여≤70세환자상당적림상획익.
Objective To explore the survival and clinical efficacy ofcolorectal cancer cases over 70 years-old receiving postoperative chemotherapy.Methods 244 colorectal cancer cases receiving postoperative chemotherapy were analyzed retrospectively.The patients were divided into two groups:over 70 years-old and below 70 years-old.The difference of overall survival between two groups was analyzed by Kaplan-Meier method and COX proportional hazard models.Results The 5 years overall survival of two groups were 63％ and 62％.No significant difference overall survival was found in two groups receiving chemotherapy.Conclusions Age is not the independent risk factor for the survival of colorectal cancer cases receiving chemotherapy.The efficacy of colorectal cancer cases over 70 years-old receiving postoperative chemotherapy is equivalent to that below 70 years-old.