中国癌症杂志
中國癌癥雜誌
중국암증잡지
CHINA ONCOLOGY
2009年
12期
947-949
,共3页
腹腔内肿瘤%放射性粒子%~(125)I
腹腔內腫瘤%放射性粒子%~(125)I
복강내종류%방사성입자%~(125)I
intraperitoneal tumor%radioactive%~(125)I seeds
背景与目的:~(125)I组织间植入术主要应用于前列腺癌治疗,近来研究表明该治疗方法在其他实体肿瘤中的治疗中亦具有一定疗效.本研究拟探讨腹腔内恶性肿瘤~(125)I组织间插植放射治疗技术及近期疗效.方法:2006年2月-2009年1月本院治疗的腹腔内恶性肿瘤20例,其中肝转移灶7例,腹膜后淋巴结转移病灶8例,胰腺癌3例,直肠癌盆腔复发2例.结果:治疗结束后2个月采用CT复查评价,局部完全缓解(CR)7例,部分缓解(PR)7例,稳定(SD)3例、进展(PD)3例,总有效率(CR+PR)70%.结论:~(125)I组织间插植放射治疗是腹腔内恶性肿瘤的有效治疗方法,近期有效率高,不良反应可以接受,远期疗效仍需进一步观察.
揹景與目的:~(125)I組織間植入術主要應用于前列腺癌治療,近來研究錶明該治療方法在其他實體腫瘤中的治療中亦具有一定療效.本研究擬探討腹腔內噁性腫瘤~(125)I組織間插植放射治療技術及近期療效.方法:2006年2月-2009年1月本院治療的腹腔內噁性腫瘤20例,其中肝轉移竈7例,腹膜後淋巴結轉移病竈8例,胰腺癌3例,直腸癌盆腔複髮2例.結果:治療結束後2箇月採用CT複查評價,跼部完全緩解(CR)7例,部分緩解(PR)7例,穩定(SD)3例、進展(PD)3例,總有效率(CR+PR)70%.結論:~(125)I組織間插植放射治療是腹腔內噁性腫瘤的有效治療方法,近期有效率高,不良反應可以接受,遠期療效仍需進一步觀察.
배경여목적:~(125)I조직간식입술주요응용우전렬선암치료,근래연구표명해치료방법재기타실체종류중적치료중역구유일정료효.본연구의탐토복강내악성종류~(125)I조직간삽식방사치료기술급근기료효.방법:2006년2월-2009년1월본원치료적복강내악성종류20례,기중간전이조7례,복막후림파결전이병조8례,이선암3례,직장암분강복발2례.결과:치료결속후2개월채용CT복사평개,국부완전완해(CR)7례,부분완해(PR)7례,은정(SD)3례、진전(PD)3례,총유효솔(CR+PR)70%.결론:~(125)I조직간삽식방사치료시복강내악성종류적유효치료방법,근기유효솔고,불량반응가이접수,원기료효잉수진일보관찰.
Background and purpose: ~(125)I seeds implantation was mainly used in the treatment of prostate cancer. Recently, this technique has been used to treat other solid tumors such as lung cancer or liver cancer. The objective of this study was to evaluate the technique and effect of interstitial brachytherapy for intraperitoneal tumors. Methods: From February 2006 to January 2009, 20 patients with intraperitoneal tumors were treated with interstitial brachytherapy. The study included 7 cases with liver metastases, 8 cases with retroperitoneal lymph nodes metastases, three cases with pancreatic cancer, 2 cases with pelvic recurrence of rectal cancer. Results: All the patients received CT scan follow up 2 months after treatment. CR, PR, SD, PD were obtained in 7, 7, 3 and 3 cases, respectively. The total response rate was 70%. Conclusion: Interstitial brachtherapy is one of the effective treatments for the patients with intraperitoneal tumor. The adverse events are tolerable but the long-term benefits of this treatment method need further study.