中华临床营养杂志
中華臨床營養雜誌
중화림상영양잡지
CHINESE JOURNAL OF CLINICAL NUTRITION
2009年
6期
343-345
,共3页
谷氨酰胺%老年%免疫功能
穀氨酰胺%老年%免疫功能
곡안선알%노년%면역공능
glutamine%elderly%immtme function
目的 观察谷氨酰胺对老年营养不良患者免疫功能的影响.方法 将24例老年营养不良患者随机分成谷氨酰胺组和对照组(每组12例),给予连续7 d等氮、等热量的肠内营养,其中谷氨酰胺组给予谷氨酰胺颗粒7.5 g每日3次口服.比较两组患者治疗前后外周静脉血IgG、IgA、IgM含量和CD3、CD4、CD8百分比及CD4/CD8比值的变化.结果 谷氨酰胺组患者外周静脉血IgG、IgA含量和CD3、CD4百分比及CD4/CD8比值均明显高于对照组(P<0.05或P<0.01).结论 谷氨酰胺能改善老年营养不良患者的免疫功能,促进康复.
目的 觀察穀氨酰胺對老年營養不良患者免疫功能的影響.方法 將24例老年營養不良患者隨機分成穀氨酰胺組和對照組(每組12例),給予連續7 d等氮、等熱量的腸內營養,其中穀氨酰胺組給予穀氨酰胺顆粒7.5 g每日3次口服.比較兩組患者治療前後外週靜脈血IgG、IgA、IgM含量和CD3、CD4、CD8百分比及CD4/CD8比值的變化.結果 穀氨酰胺組患者外週靜脈血IgG、IgA含量和CD3、CD4百分比及CD4/CD8比值均明顯高于對照組(P<0.05或P<0.01).結論 穀氨酰胺能改善老年營養不良患者的免疫功能,促進康複.
목적 관찰곡안선알대노년영양불량환자면역공능적영향.방법 장24례노년영양불량환자수궤분성곡안선알조화대조조(매조12례),급여련속7 d등담、등열량적장내영양,기중곡안선알조급여곡안선알과립7.5 g매일3차구복.비교량조환자치료전후외주정맥혈IgG、IgA、IgM함량화CD3、CD4、CD8백분비급CD4/CD8비치적변화.결과 곡안선알조환자외주정맥혈IgG、IgA함량화CD3、CD4백분비급CD4/CD8비치균명현고우대조조(P<0.05혹P<0.01).결론 곡안선알능개선노년영양불량환자적면역공능,촉진강복.
Objective To evaluate the effects of glutamine on immune function in elderly patients with malnutrition.Methods Twenty-four elderly patients with malnutrition were equally randomized divided into glutamine group and control group.Patients in both two groups were administered with enteral nutrition containing equal nitrogen and calorics for consecutively 7 days.In the glutamine group,patients were also supplied with oral glutamine (7.5g tid).Changes of plasma IgG,IgA,and IgM levels,percentages of T-lymphocyte subsets (CD3,CD4,CD8),and CD4/CD8 ratio were determined before and after treatment.Results Plasma IgG and IgA lev-els,percentages of CD3 and CD4,and CD4/CD8 ratio were significantly higher in glutamine group than in control group (P<0.05 or P<0.01).Conclusion Glutamine can improve the immune function in elderly patients with malnutritiop and promote their recovery.
