CAJ | 학술논문

目的探讨正电子发射断层显像-计算机断层显像(PET-CT)在鼻咽癌远处转移诊断和M分期中的价值.方法 257例初治鼻咽癌患者于治疗前行胸部X线摄片、腹部B型超声检查、骨发射单光子计算机断层扫描(ECT)等常规检查和PET-CT扫描.依据病理活检和随访结果比较PET-CT和常规检查在远处转移诊断和M分期中的作用.结果 39例(15.2%)鼻咽癌存在远处转移,其中PET-CT检出34例,而常规检查仅检出22例.PET-CT假阳性率为12.8%(5/39).若按转移灶分布部位分析,PET-CT 能提高纵隔转移检出率(x2=4.063,P=0.041)和骨转移的检出率(x2=5.939,P=0.015).与常规检查相比,PET-CT改变了19例(7.4%)患者的M分期,判断正确14例,判断错误5例.结论 PET-CT判断鼻咽癌远处转移和M分期较常规检查准确.
목적 탐토정전자발사단층현상-계산궤단층현상(PET-CT)재비인암원처전이진단화M분기중적개치.방법 257례초치비인암환자우치료전행흉부X선섭편、복부B형초성검사、골발사단광자계산궤단층소묘(ECT)등상규검사화PET-CT소묘.의거병리활검화수방결과비교PET-CT화상규검사재원처전이진단화M분기중적작용.결과 39례(15.2%)비인암존재원처전이,기중PET-CT검출34례,이상규검사부검출22례.PET-CT가양성솔위12.8%(5/39).약안전이조분포부위분석,PET-CT 능제고종격전이검출솔(x2=4.063,P=0.041)화골전이적검출솔(x2=5.939,P=0.015).여상규검사상비,PET-CT개변료19례(7.4%)환자적M분기,판단정학14례,판단착오5례.결론 PET-CT판단비인암원처전이화M분기교상규검사준학.
Objective To explore the clinical significance of PET-CT in evaluating distant metastasis and M staging of nasopharyngeal carcinoma(NPC). Methods 257 NPC patients with no prior treatment were investigated with PET-CT and conventional imaging (chest X-ray, abdominal ultrasound, and bone scan). The findings of PET-CT in diagnosing distant metastasis and M staging were compared with those of conventional imaging according to the results of biopsy and follow-up. Results PET-CT disclosed 34 of 39 patients with distant malignancy compared with 22 patients disclosed by conventional imaging. The false positive rate of PET-CT was 12.8 %. On region-based analyses, PET-CT was more effective than bone scan and chest X-ray for detecting mediastinum metastasis (x2=4.063, P =0.041) and bone metastasis (x2=5.939, P=0.015), respectively. Compared with conventional imaging, PET-CT had an impact on the M staging of 19 patients (7.4 %), of which 15 patients were truly staged and 4 patients incorrectly staged. Conclusion PET-CT is superior to MRI in evaluating distant metastasis and M staging of NPC.