国际皮肤性病学杂志
國際皮膚性病學雜誌
국제피부성병학잡지
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
2012年
4期
214-216
,共3页
结节病%皮肤%瘢痕%病例报告
結節病%皮膚%瘢痕%病例報告
결절병%피부%반흔%병례보고
Sarcoidosis%Skin%Cicatrix%Case reports
患者女,31岁.因左上唇及左额部外伤瘢痕4年余,局部斑块3个月就诊.皮肤科检查:左上唇、额部皮肤分别见2cm×3.5 cm和1.5 cm×1.5 cm的斑块,色淡红,边界清楚,质硬.皮损组织病理检查:真皮内可见大小不一的细胞团块,由上皮样细胞及少许多核巨细胞构成,无明显干酪样坏死.PAS、PAM 及抗酸染色阴性,各系统实验室检查未见异常.诊断:瘢痕性结节病.予激光磨削术,口服甲泼尼龙、匹多莫德和阿奇霉素综合治疗,取得良好疗效.随访1年,治疗区局部平整,且恢复正常肤色.
患者女,31歲.因左上脣及左額部外傷瘢痕4年餘,跼部斑塊3箇月就診.皮膚科檢查:左上脣、額部皮膚分彆見2cm×3.5 cm和1.5 cm×1.5 cm的斑塊,色淡紅,邊界清楚,質硬.皮損組織病理檢查:真皮內可見大小不一的細胞糰塊,由上皮樣細胞及少許多覈巨細胞構成,無明顯榦酪樣壞死.PAS、PAM 及抗痠染色陰性,各繫統實驗室檢查未見異常.診斷:瘢痕性結節病.予激光磨削術,口服甲潑尼龍、匹多莫德和阿奇黴素綜閤治療,取得良好療效.隨訪1年,治療區跼部平整,且恢複正常膚色.
환자녀,31세.인좌상진급좌액부외상반흔4년여,국부반괴3개월취진.피부과검사:좌상진、액부피부분별견2cm×3.5 cm화1.5 cm×1.5 cm적반괴,색담홍,변계청초,질경.피손조직병리검사:진피내가견대소불일적세포단괴,유상피양세포급소허다핵거세포구성,무명현간락양배사.PAS、PAM 급항산염색음성,각계통실험실검사미견이상.진단:반흔성결절병.여격광마삭술,구복갑발니룡、필다막덕화아기매소종합치료,취득량호료효.수방1년,치료구국부평정,차회복정상부색.
A 31-year-old female patient was admitted to the hospital for traumatic scars in the left upper lip and forehead for more than 4 years and localized plaques for 3 months.Skin examination revealed 2 slightly erythematous,well-marginated,indurated plaques sized 2 cm × 3.5 cm and 1.5 cm × 1.5cm respectively in the left upper lip and forehead.Histopathology of the lesions revealed varying sizes of cell clumps composed of epithelioid cells and a few multinucleated giant cells in the dermis,while no obvious caseous necrosis was found.In addition,periodic acid-Schiff (PAS)staining,periodic acid methenamine silver (PAM) staining and acid-fast staining were negative.Laboratory tests revealed no abnormality in other organ systems.The patient was diagnosed with scar sarcoidosis,and treated with laser resurfacing as well as oral methylprednisolone,pidotimod and azithromycin,which resulted in a satisfactory outcome.After one-year follow-up,the lesion was flattened with a return to normal skin colour.