CAJ | 학술논문

目的应用血流向量成像(VFM)显示左室内血流变化情况,观察血流在心肌梗死节段运动状态并量化分析其改变,评价心肌梗死状态对心腔内血流的影响.方法选取陈旧性心肌梗死患者28例,正常对照30例为观察对象,利用VFM技术采集左心室内血流向量图像,应用VFM分析软件DSA-RS1测量心尖左室长轴观及心尖四腔观不同节段时间-流量(T-F)的变化及在收缩与舒张期峰值处相应的血流参数:垂直于取样线方向的向量速度测值(NVP),平行于取样线方向的向量速度测值(PVP),取样线上综合向量测值(VP),取样线所通过的流量测值(FP)变化情况.结果 T-F曲线显示心肌梗死节段收缩期峰值S、舒张期峰值E、心房收缩期峰值A较正常对照组均明显减低,时间延迟(P＜0.05).心肌梗死节段收缩期峰值S及舒张期峰值E处相应的血流参数PVP及FP均有所减低(P＜0.05).结论心肌梗死患者心肌梗死节段血流速度较正常节段明显减低,达峰时间延长,VFM是一种有效的评价心肌梗死患者梗死节段室壁运动异常所引起的血流动力学变化的新方法.
목적 응용혈류향량성상(VFM)현시좌실내혈류변화정황,관찰혈류재심기경사절단운동상태병양화분석기개변,평개심기경사상태대심강내혈류적영향.방법 선취진구성심기경사환자28례,정상대조30례위관찰대상,이용VFM기술채집좌심실내혈류향량도상,응용VFM분석연건DSA-RS1측량심첨좌실장축관급심첨사강관불동절단시간-류량(T-F)적변화급재수축여서장기봉치처상응적혈류삼수:수직우취양선방향적향량속도측치(NVP),평행우취양선방향적향량속도측치(PVP),취양선상종합향량측치(VP),취양선소통과적류량측치(FP)변화정황.결과 T-F곡선현시심기경사절단수축기봉치S、서장기봉치E、심방수축기봉치A교정상대조조균명현감저,시간연지(P＜0.05).심기경사절단수축기봉치S급서장기봉치E처상응적혈류삼수PVP급FP균유소감저(P＜0.05).결론 심기경사환자심기경사절단혈류속도교정상절단명현감저,체봉시간연장,VFM시일충유효적평개심기경사환자경사절단실벽운동이상소인기적혈류동역학변화적신방법.
Objective To evaluate blood flow structure within left ventricle,quantify the variation of the flow at infarct segments,and assess the impact of myocardial infarction.Methods Twenty-eight patients with chronic myocardial infarction(CMI)and 30 healthy controls were involved.The flow vector images on the section plane of the flow within the left ventricle were acquired by vector flow mapping(VFM).Timeflow(T-F)curve and all other peak systolic and diastolic flow curve include normal velocity profile,parallel velocity profile,vector profile were analyzed by DSA-RSI program.Results Ventricular ejction peak S,rapid ventricular filling peak E and atrial systole peak A were relatively lower in CMI group at infarct segment than normal control group,the time duration from bottom to peak was relatively longer in CMI group.Normal velocity profile,parallel velocity profile,vector profile,flow profile at peak S and E were lower in CMI group than normal group.Conclusions The velocity of CMI group was lower and the time to peak was longer than that of control group.VFM is a new noninvasive and clinically useful parameter for the evaluation of regional left ventricular segment flow dynamics.