CAJ | 학술논문

目的探讨常见影响因素对冠状动脉粥样硬化形成的危险性,为临床防治提供科学依据.方法选择2005年6月-2009年1月入住我院的疑诊冠心病并行CT血管成像(CTA)检查的患者276例,根据冠脉CTA结果将其分为正常、轻度粥样硬化及冠心病三组,用卡方检验和多元Logistic回归分析对其常见影响因素进行分析.结果单因素回归分析显示:年龄(χ~2=14.394,P=-0.006)、高血压(χ~2=6.445,p=0.040)、总胆同醇(χ~2=8.464,P=0.015)、甘油三酯(χ~2=7.084,P=-0.029)、低密度脂蛋白(χ~2=6.399,P=-0.041)对冠状动脉粥样硬化形成有影响;多元logistic回归分析后发现年龄(Wald=14.433,P=-0.000)、吸烟(Wald=7.425,P=-0.007)及总胆同醇(Wald=4.637,P=0.031)对冠状动脉粥样硬化形成的影响较其它因素更大.结论本研究发现年龄、吸烟及总胆固醇是影响冠状动脉粥样硬化的主要危险因素,针对可控危险因素给予积极有效的控制,为患者提供个性化健康教育,改变不良的行为和生活方式.提高治疗依从性.能更有效地预防冠心病的发生.
목적 탐토상견영향인소대관상동맥죽양경화형성적위험성,위림상방치제공과학의거.방법 선택2005년6월-2009년1월입주아원적의진관심병병행CT혈관성상(CTA)검사적환자276례,근거관맥CTA결과장기분위정상、경도죽양경화급관심병삼조,용잡방검험화다원Logistic회귀분석대기상견영향인소진행분석.결과 단인소회귀분석현시:년령(χ~2=14.394,P=-0.006)、고혈압(χ~2=6.445,p=0.040)、총담동순(χ~2=8.464,P=0.015)、감유삼지(χ~2=7.084,P=-0.029)、저밀도지단백(χ~2=6.399,P=-0.041)대관상동맥죽양경화형성유영향;다원logistic회귀분석후발현년령(Wald=14.433,P=-0.000)、흡연(Wald=7.425,P=-0.007)급총담동순(Wald=4.637,P=0.031)대관상동맥죽양경화형성적영향교기타인소경대.결론 본연구발현년령、흡연급총담고순시영향관상동맥죽양경화적주요위험인소,침대가공위험인소급여적겁유효적공제,위환자제공개성화건강교육,개변불량적행위화생활방식.제고치료의종성.능경유효지예방관심병적발생.
Objective Depth analysis of common factors on the formation of coronary atherosclerosis risk, Providing a scientific basis for clinical prevention and treatment.Methods Selected in June 2005 ～ January 2009 stay at our hospital diagnosed as coronary heart disease concurrent CTA examined 276 cases of patients, according to the results of coronary CTA will be divided into normal, mild atherosclerosis and coronary heart disease 3 groups, using chi-square test and Logistic regression analysis of multiple factors affecting their common-depth analysis. Results The results of univariate regression analysis showed that: age (χ~2=14.394, P= 0.006), hypertension (χ~ 2 = 6.445, P=0. 040), total cholesterol (x~2 = 8.464, P= 0.015), triglycerides (χ~2 = 7.084, P=0.029), low-density lipoprotein (χ~2= 6.399, P= 0.041) on the formation of coronary atherosclerosis affected; multiple logistic regression analysis showed that age (Wald = 14.433, P= 0.000), smoking (Wald = 7. 425, P= 0.007) and total cholesterol (Wald = 4.637, P= 0.031) of coronary atherosclerosis than other factors affecting the formation of a greater.Conclusion This study found that age, smoking and total cholesterol, affecting the coronary atherosclerosis of the major risk factors, controllable risk factors for positive and effective control, in order to provide patients with personalized health education to change unhealthy behavior and lifestyles, to improve treatment compliance would be more effective in preventing the occurrence of coronary heart disease.