CAJ | 학술논문

目的探讨大脑灰质异位(HGM)与癫痫的关系,以及手术治疗的价值. 方法回顾性分析解放军第四五八医院神经外科自2004年5月至2006年5月收治的6例HGM所致癫痫患者的临床特点、手术方式以及随访结果. 结果 6例患者中,4例行异位灰顶切除+皮层热灼,1例行异位灰顶切除+皮层热灼+前颞叶切除.1例行单纯皮层热灼.术后随访2～4年,5例至今未见发作,1例发作明显缓解. 结论对于HGM所致的难治性癫痫,外科手术是一个有效的治疗方法.
목적 탐토대뇌회질이위(HGM)여전간적관계,이급수술치료적개치. 방법 회고성분석해방군제사오팔의원신경외과자2004년5월지2006년5월수치적6례HGM소치전간환자적림상특점、수술방식이급수방결과. 결과 6례환자중,4례행이위회정절제+피층열작,1례행이위회정절제+피층열작+전섭협절제.1례행단순피층열작.술후수방2～4년,5례지금미견발작,1례발작명현완해. 결론 대우HGM소치적난치성전간,외과수술시일개유효적치료방법.
Objective To explore the relationship between gray matter heterotopia and epilepsy and assess the therapeutic effect of surgical intervention. Methods Six cases of gray matter heterotopia-induced epilepsy treated in our department between May, 2004 and May, 2006 were analyzed retrospectively for the clinical characteristics, surgical approaches, and the outcomes in the 2- to 4-year-long follow-up. Results All the patients received surgical interventions through different approaches, including resection of the heterotopic gray matter plus bipolar coagulation of the cortexes in 4 cases, heterotopic gray matter resection with bipolar coagulation of the cortexes and temporal lobectomy in 1 case, and exclusive bipolar coagulation of the cortexes in 1 case. Five patients were free of seizure attach and 1 patient showed significantly reduced seizure attack after the operation. Conclusion Surgical intervention can be effective for treatment of intractable epilepsy induced by gray matter heterotopia.