CAJ | 학술논문

目的探讨18F-脱氧葡萄糖(FDG)PET延迟显像对肺良恶性病变的鉴别诊断价值.方法对36例肺癌患者和20例肺良性病变患者分别进行18F-FDG PET早期头部至盆腔显像和注射后3h胸部延迟显像,测定两次显像病灶的标准摄取值(SUV),并计算18F-FDG的储留指数(砌).结果肺癌组延迟显像SUV明显高于肺良性病变组(P<0.01).肺癌组的砌也明显高于肺良性病变组(P<0.01);对于早期显像SUV>2.5的肺部结节,以RI>20%为阈值,延迟显像对肺良恶性病变鉴别诊断的灵敏度、特异性和准确性分别为90.0%、80.0%和86.7%.结论 18F-FDG PET延迟显像有助于肺良恶性病变的鉴别诊断,结合应用SUV及RI两项指标可提高诊断准确率.
목적 탐토18F-탈양포도당(FDG)PET연지현상대폐량악성병변적감별진단개치.방법 대36례폐암환자화20례폐량성병변환자분별진행18F-FDG PET조기두부지분강현상화주사후3h흉부연지현상,측정량차현상병조적표준섭취치(SUV),병계산18F-FDG적저류지수(체).결과 폐암조연지현상SUV명현고우폐량성병변조(P<0.01).폐암조적체야명현고우폐량성병변조(P<0.01);대우조기현상SUV>2.5적폐부결절,이RI>20%위역치,연지현상대폐량악성병변감별진단적령민도、특이성화준학성분별위90.0%、80.0%화86.7%.결론 18F-FDG PET연지현상유조우폐량악성병변적감별진단,결합응용SUV급RI량항지표가제고진단준학솔.
Objective To explore the value of 18F-FDG PET delayed imaging in differentiation of malignant from benign lung nodules. Methods Thirty-six patients with malignant lung lesions and 20 patients with benign lesions underwent 18F-FDG PET early and 3h delayed imaging after intravenous injection of FDG. The standardized uptake value(SUV) was calculated for both time points, and retention index(RI) was also calculated. Results The SUV and RI of the lesions were significantly higher in lung cancer group than in. benign lung nodules group(P<0.01). Take SUV>2.5 combining RI as standard,the sensitivity, speciality and accuracy of delayed imaging in differentiation of malignant from benign lung nodules was 90. 0%, 80. 0% and 86.7% respectively. Conclusion 18F-FDG PET delayed imaging is a reliable imaging protocol for differentiating malignant from benign lung nodules. Delayed imaging combining SUV and RI can improve the accuracy of diagnosis.