临床医学工程
臨床醫學工程
림상의학공정
CLINICAL MEDICAL ENGINEERING
2009年
7期
39-41
,共3页
药物不良反应%临床药学%分析%评价
藥物不良反應%臨床藥學%分析%評價
약물불량반응%림상약학%분석%평개
Adverse Drug Reaction%Clinical Pharmacy%Analysis%Evaluation
目的 了解药物不良反应(ADR)的发生情况和原因,为临床合理用药和药物安全性评价提供依据.方法 对我院ADR监测中心近年来收到并网上直报的292例ADR报告进行统计分析及评价.结果 292例报告中男性患者ADK发生率最高,占60%以上,年龄以19-29岁患者居多,占94例(32.19%);引起ADR的用药途径以静脉滴注为主,共233例(79.8%),药物剂型以注射剂(138例,47.26%)和粉针剂(104例,35.62%)居多.ADR的主要临床表现以皮肤损害为主,占59.92%(175例),最易引起ADK的药物是抗感染药物,占56.85%(166例).结论 ADK发生与诸多因素有关,临床表现多样化,需加强ADK的监测,提高ADR的预防、诊断和治疗,以保证安全合理用药.
目的 瞭解藥物不良反應(ADR)的髮生情況和原因,為臨床閤理用藥和藥物安全性評價提供依據.方法 對我院ADR鑑測中心近年來收到併網上直報的292例ADR報告進行統計分析及評價.結果 292例報告中男性患者ADK髮生率最高,佔60%以上,年齡以19-29歲患者居多,佔94例(32.19%);引起ADR的用藥途徑以靜脈滴註為主,共233例(79.8%),藥物劑型以註射劑(138例,47.26%)和粉針劑(104例,35.62%)居多.ADR的主要臨床錶現以皮膚損害為主,佔59.92%(175例),最易引起ADK的藥物是抗感染藥物,佔56.85%(166例).結論 ADK髮生與諸多因素有關,臨床錶現多樣化,需加彊ADK的鑑測,提高ADR的預防、診斷和治療,以保證安全閤理用藥.
목적 료해약물불량반응(ADR)적발생정황화원인,위림상합리용약화약물안전성평개제공의거.방법 대아원ADR감측중심근년래수도병망상직보적292례ADR보고진행통계분석급평개.결과 292례보고중남성환자ADK발생솔최고,점60%이상,년령이19-29세환자거다,점94례(32.19%);인기ADR적용약도경이정맥적주위주,공233례(79.8%),약물제형이주사제(138례,47.26%)화분침제(104례,35.62%)거다.ADR적주요림상표현이피부손해위주,점59.92%(175례),최역인기ADK적약물시항감염약물,점56.85%(166례).결론 ADK발생여제다인소유관,림상표현다양화,수가강ADK적감측,제고ADR적예방、진단화치료,이보증안전합리용약.
Objective To study the causes of ADR oeettrred in our hospital and to provide the evidences of drug security and rational clinical drug use. Methods 292 ADR cases collected during recent years in our hospital were analyzed statistically using a descriptive study method. Results It was the highest occurrence rate in the group of people who were 19-29 years old male-patients, accounting for 32.19% (94 cases). The intravenous medication was the main route of medication resulting in ADR accounting for 79.8% (233 cases). It was highest occur-rence rate in the group of drug which types are injection (138 eases, 47.26%) and parenteral solution (104 cases, 35.62%). ADR were mainly manifested as lesions of skin, accounting for 59.92 %(175cases). It was the easiest occurrence in the group of anti-infective, accounting for 56. 85%(166 cases). Conclusion ADR occurs with a number of factors related to the diversification of clinical manifestations. ADR monitoring should be strengthened to improve the prevention, diagnosis and treatment of ADR so as to ensure the securities and rational clinical drug use.
