CAJ | 학술논문

目的研究影响乙肝免疫效果的因素,探讨提高乙肝免疫预防效果的方法 .方法使用巢式病例对照研究方法 ,以2006年全国乙肝等疾病血清流行病调查河北现场的1734名1-15岁儿童作为研究对象,按其HBsAg是否阳性分为病例组和对照组,分析造成儿童HBsA9阳性的危险因素.结果母亲HBsAg阳性和儿童年龄、出生医院是影响乙肝疫苗预防效果的主要因素(P<0.0001).结论当前乙肝免疫预防的工作重点在于发现HBsAg阳性孕妇,同时改进农村地区的新生儿乙肝免疫预防条件.
목적 연구영향을간면역효과적인소,탐토제고을간면역예방효과적방법 .방법 사용소식병례대조연구방법 ,이2006년전국을간등질병혈청류행병조사하북현장적1734명1-15세인동작위연구대상,안기HBsAg시부양성분위병례조화대조조,분석조성인동HBsA9양성적위험인소.결과 모친HBsAg양성화인동년령、출생의원시영향을간역묘예방효과적주요인소(P<0.0001).결론 당전을간면역예방적공작중점재우발현HBsAg양성잉부,동시개진농촌지구적신생인을간면역예방조건.
Objective Study the risk factors that impact the effectiveness of mass hepatitis B vaccination, and try to amend them in the future. Method Based on the national surveillance of hepatitis B, all the 1734 of 1-15 years old children from Hebei Province were enrolled in the present study and they were divided into case and control group according to their sera HBsAg were positive or not. Results Mother sera HBsAg positive and the hospital the children were born and earlier year of birth were risk factors. Conclusion The effectiveness of mass neonate hepatitis B vaccination has greatly improved and the future focus should be on finding pregnant HBsAg positive women, and encourage them to give birth in better hospitals, and at the mean time, try to make the neonate hepatitis B vaccination perfect, especially in country areas.