CAJ | 학술논문

目的探讨乳腺癌腋淋巴结转移的影响因素.方法回顾性分析2006年12月至2008年11月在山西省肿瘤医院诊治的乳腺癌患者.采用Logistic回归分析,检查乳腺癌腋淋巴结转移与患者年龄、肿瘤大小、肿瘤病理类型、雌激素受体(ER)、孕激素受体(PR)、人类表皮生长因子受体2(Her-2)等因素的关系.结果 1133例乳腺癌患者中,具有完整的腋淋巴结手术及其他临床病理资料者787例(69.5%).平均每例清扫淋巴结14.6枚,平均每例淋巴结转移3.5枚.肿瘤大小与淋巴结转移呈正相关.多变量Logistic回归分析显示,患者年龄、肿瘤大小、ER状态、肿瘤病理类型与乳腺癌腋淋巴结转移有显著的相关性(P<0.05).结论肿瘤大小、患者年龄、ER状态及病理类型是乳腺癌腋窝淋巴结转移的影响因素.
목적 탐토유선암액림파결전이적영향인소.방법 회고성분석2006년12월지2008년11월재산서성종류의원진치적유선암환자.채용Logistic회귀분석,검사유선암액림파결전이여환자년령、종류대소、종류병리류형、자격소수체(ER)、잉격소수체(PR)、인류표피생장인자수체2(Her-2)등인소적관계.결과 1133례유선암환자중,구유완정적액림파결수술급기타림상병리자료자787례(69.5%).평균매례청소림파결14.6매,평균매례림파결전이3.5매.종류대소여림파결전이정정상관.다변량Logistic회귀분석현시,환자년령、종류대소、ER상태、종류병리류형여유선암액림파결전이유현저적상관성(P<0.05).결론 종류대소、환자년령、ER상태급병리류형시유선암액와림파결전이적영향인소.
Objective To explore the predictors of axillary nodal metastass in patients with breast cancer.Methods A retrospective study was performed using the clinicopathological data of breast cancer cases diagnosed and treated in our Hospital between Dec 2006 and Nov 2008.Logistic regression analysis was used to determine the predictors of axillary node positivity.Results The total number of patients was 1133.69.5% of them (787) had complete clinical and pathological data.The median age was 49 years old ( range 20-85 ).The average number of lymph nodes removed was 14.6 per person.The average number of involved nodes was 3.5 per person.Increasing tumor size was associated with increased risk of lymph node metastases.Assessed by multivariate analysis, the tumor size, age, ER status, and pathological type were significantly associated with node metastasis.Conclusions Axillary nodal metastases are significantly affected by the tumor size, ER status, age, and pathological type in breast cancer patients.