中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2012年
2期
106-109
,共4页
康锴%唐晓燕%许汴利%尤爱国%黄学勇%杜燕华%王海峰%赵国华%陈豪敏%刘国华%孟凡俊
康鍇%唐曉燕%許汴利%尤愛國%黃學勇%杜燕華%王海峰%趙國華%陳豪敏%劉國華%孟凡俊
강개%당효연%허변리%우애국%황학용%두연화%왕해봉%조국화%진호민%류국화%맹범준
人群监测%流行病学%发热%血小板减少%综合征%新布尼亚病毒
人群鑑測%流行病學%髮熱%血小闆減少%綜閤徵%新佈尼亞病毒
인군감측%류행병학%발열%혈소판감소%종합정%신포니아병독
Population surveillance%Epidemiology%Fever%Thrombocytopenia%Syndrome%New bunyavirus
目的 分析河南省2007-2011年发热伴血小板减少综合征流行病学特征.方法 数据来源于河南省发热伴血小板减少综合征专项监测系统和中国疾病预防控制信息管理系统,利用描述流行病学对2007-2011年监测数据进行分析.采集病例血清标本,开展新布尼亚病毒实时荧光RTPCR检测和病毒分离.结果 河南省2007-2011年共报告发热伴血小板减少综合征病例1021例,死亡23例,病死率为2.25％.其中信阳市报告1007例,占98.75％.病例主要集中在4-10月,占96.47％(985/1021),5-7月为高峰,占59.16％(604/1021),9月出现第2个发病高峰,占12.05％(123/1021).病例年龄中位数为59岁(范围为1～ 88岁),男女性别比为1∶1.50(408∶613),农民占全部病例的93.73％(957/1021).465例病例血液标本中新布尼亚病毒核酸阳性率为69.25％(322/465),从164例血液标本中分离到新布尼亚病毒67株,分离率为40.85％(67/164).结论 河南省发热伴血小板减少综合征发病具有一定的地域性和季节性,大年龄组女性农民高发,新布尼亚病毒为其主要病原.
目的 分析河南省2007-2011年髮熱伴血小闆減少綜閤徵流行病學特徵.方法 數據來源于河南省髮熱伴血小闆減少綜閤徵專項鑑測繫統和中國疾病預防控製信息管理繫統,利用描述流行病學對2007-2011年鑑測數據進行分析.採集病例血清標本,開展新佈尼亞病毒實時熒光RTPCR檢測和病毒分離.結果 河南省2007-2011年共報告髮熱伴血小闆減少綜閤徵病例1021例,死亡23例,病死率為2.25％.其中信暘市報告1007例,佔98.75％.病例主要集中在4-10月,佔96.47％(985/1021),5-7月為高峰,佔59.16％(604/1021),9月齣現第2箇髮病高峰,佔12.05％(123/1021).病例年齡中位數為59歲(範圍為1～ 88歲),男女性彆比為1∶1.50(408∶613),農民佔全部病例的93.73％(957/1021).465例病例血液標本中新佈尼亞病毒覈痠暘性率為69.25％(322/465),從164例血液標本中分離到新佈尼亞病毒67株,分離率為40.85％(67/164).結論 河南省髮熱伴血小闆減少綜閤徵髮病具有一定的地域性和季節性,大年齡組女性農民高髮,新佈尼亞病毒為其主要病原.
목적 분석하남성2007-2011년발열반혈소판감소종합정류행병학특정.방법 수거래원우하남성발열반혈소판감소종합정전항감측계통화중국질병예방공제신식관리계통,이용묘술류행병학대2007-2011년감측수거진행분석.채집병례혈청표본,개전신포니아병독실시형광RTPCR검측화병독분리.결과 하남성2007-2011년공보고발열반혈소판감소종합정병례1021례,사망23례,병사솔위2.25％.기중신양시보고1007례,점98.75％.병례주요집중재4-10월,점96.47％(985/1021),5-7월위고봉,점59.16％(604/1021),9월출현제2개발병고봉,점12.05％(123/1021).병례년령중위수위59세(범위위1～ 88세),남녀성별비위1∶1.50(408∶613),농민점전부병례적93.73％(957/1021).465례병례혈액표본중신포니아병독핵산양성솔위69.25％(322/465),종164례혈액표본중분리도신포니아병독67주,분리솔위40.85％(67/164).결론 하남성발열반혈소판감소종합정발병구유일정적지역성화계절성,대년령조녀성농민고발,신포니아병독위기주요병원.
Objective To analyze the epidemiological characteristics of fever thrombocytopenia and leukopenia syndrome(FTLS)in Henan province,China in 2007-2011.Methods Data from specific surveillance system for FTLS in Henan and Information Management System of Chinese Center for Disease Control and Prevention were used to collect the information of the cases.Descriptive epidemiological methods were used to analyze the surveillance data during 2007-2011.Patients' sera were collected to detect new bunyavirus using fluorescent RT-PCR and virus isolation.Results During 2007-2011,1021 FTLS cases were reported in Henan province.The fatality rate was 2.25％ with 23 deaths.The cases reported in Xinyang city were 1007,accounting for 98.75％.Cases were mainly occurred between April and October,accounting for 96.47％(985/1021).Epidemic peak was May to July,accounting for 59.16％(604/1021).The second peak occurred in September,accounting for 12.05％(123/1021).The age of the cases ranged from 1 to 88 years old with the median age of 59.Sex ratio(male:female)was 1:1.50(408:613).In all cases,93.73％(957/1021)were farmers.In 465 patients' sera,the positive rate of new bunyavirus was 69.25％(322/465)using fluorescent RT-PCR.In 164 patients' sera,67 strains of new bunyavirus were isolated with isolation rate of 40.85％(67/164).Conclusion FTLS in Henan province is caused mainly by the new bunyavirus and has certain regional and seasonal characteristics.Most cases are female older farmers.
