CAJ | 학술논문

目的为了观察人工肝支持系统在肝移植围手术期中的应用情况.方法对1例晚期肝硬变伴小肝癌患者施行同种异体原位肝移植,术前术后共进行8次人工肝支持系统治疗,移植术中无肝期采用体外静脉转流技术,术后应用甲基泼尼松龙和环孢素A进行免疫抑制.结果患者术后早期恢复顺利,但手术后21天死于颅内出血.结论认为术前使用人工肝支持系统能改善患者一般情况,使更易耐受手术,并可在急性肝功能衰竭患者等待供肝时使用;术后使用能改善患者生理紊乱状况,并帮助渡过急性排斥反应期.
목적 위료관찰인공간지지계통재간이식위수술기중적응용정황.방법 대1례만기간경변반소간암환자시행동충이체원위간이식,술전술후공진행8차인공간지지계통치료,이식술중무간기채용체외정맥전류기술,술후응용갑기발니송룡화배포소A진행면역억제.결과 환자술후조기회복순리,단수술후21천사우로내출혈.결론 인위술전사용인공간지지계통능개선환자일반정황,사경역내수수술,병가재급성간공능쇠갈환자등대공간시사용;술후사용능개선환자생리문란상황,병방조도과급성배척반응기.
Objective To investigate the application of artificial liver support system during the perioperation of orthotopic liver transplantation. Methods One patient with end-stage liver cirrhosis with liver cancer successfully underwent orthotopic liver transplantation. The patient received artificial liver support system (ALSS) treatment 8 times before and after operation. The recipients' operation was performed under the veno-venous bypass procedure. The double-drug immunosuppressive regimen , methylprodnisolone and cyclosporine A, was used after operation. Results The patient had a smooth recovery in the early stage and died of intracerebral hemorrhage at the 21st postoperative day. Conclusion ALSS treatment can improve general conditions of the patient before operation, and correct physiological disturbances and help to survive during immune rejection after operation.