中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
3期
264-266
,共3页
郑霄云%郑知刚%闫少西%金江丽%李靖%王希
鄭霄雲%鄭知剛%閆少西%金江麗%李靖%王希
정소운%정지강%염소서%금강려%리정%왕희
原发性高血压病%心室功能,右%超声心动描记术,多普勒%Tei指数
原髮性高血壓病%心室功能,右%超聲心動描記術,多普勒%Tei指數
원발성고혈압병%심실공능,우%초성심동묘기술,다보륵%Tei지수
Essential hypertension%Ventricular function,right%Echocardiography,Doppler%Tei index
目的 应用组织多普勒成像(TDI)技术检测Tei指数(TDI-Tei)及三尖瓣环运动速度参数,评价原发性高血压病患者右心室功能的变化.方法 选取140例原发性高血压病患者,其中左心室肥厚(LVH)组69例,非左心室肥厚(NLVH)组71例,另外选取正常健康者50例作为对照组.脉冲多普勒测量三尖瓣口舒张早期血流速度(E)、舒张晚期血流速度(A),计算E/A比值；脉冲TDI测量右心室侧壁三尖瓣环处的TDI-Tei及收缩期峰值运动速度(Sm)、舒张早期峰值运动速度(Em)、舒张晚期峰值运动速度(Am),计算Em/Am比值.结果 LVH组与NLVH组Em[(8.9±2.4)、(11.2±2.5)cm/s]、Em/Am比值[0.56±0.15、0.76±0.16]均明显低于对照组[分别为(13.1±3.2)cm/s、0.93±0.19],差异均有统计学意义(均P＜0.05).LVH组与NLVH组TDI-Tei(0.54±0.12、0.41 ±0.08)均明显高于对照组(0.33±0.06),差异有统计学意义(P＜0.05).LVH组Sm[( 12.3±2.3)cm/s]明显低于对照组[(13.8±2.3)cm/s],差异有统计学意义(P＜0.05).LVH组与NLVH组TDI-Tei与E/A比值、Em、Em/Am比值和Sm呈明显负相关(分别为r=-0.412、r=-0.526、r=-0.498、r=-0.371,P＜0.01).结论 TDI-Tei联合三尖瓣环运动速度参数能够客观、全面地评价原发性高血压病患者的右心室功能障碍.
目的 應用組織多普勒成像(TDI)技術檢測Tei指數(TDI-Tei)及三尖瓣環運動速度參數,評價原髮性高血壓病患者右心室功能的變化.方法 選取140例原髮性高血壓病患者,其中左心室肥厚(LVH)組69例,非左心室肥厚(NLVH)組71例,另外選取正常健康者50例作為對照組.脈遲多普勒測量三尖瓣口舒張早期血流速度(E)、舒張晚期血流速度(A),計算E/A比值；脈遲TDI測量右心室側壁三尖瓣環處的TDI-Tei及收縮期峰值運動速度(Sm)、舒張早期峰值運動速度(Em)、舒張晚期峰值運動速度(Am),計算Em/Am比值.結果 LVH組與NLVH組Em[(8.9±2.4)、(11.2±2.5)cm/s]、Em/Am比值[0.56±0.15、0.76±0.16]均明顯低于對照組[分彆為(13.1±3.2)cm/s、0.93±0.19],差異均有統計學意義(均P＜0.05).LVH組與NLVH組TDI-Tei(0.54±0.12、0.41 ±0.08)均明顯高于對照組(0.33±0.06),差異有統計學意義(P＜0.05).LVH組Sm[( 12.3±2.3)cm/s]明顯低于對照組[(13.8±2.3)cm/s],差異有統計學意義(P＜0.05).LVH組與NLVH組TDI-Tei與E/A比值、Em、Em/Am比值和Sm呈明顯負相關(分彆為r=-0.412、r=-0.526、r=-0.498、r=-0.371,P＜0.01).結論 TDI-Tei聯閤三尖瓣環運動速度參數能夠客觀、全麵地評價原髮性高血壓病患者的右心室功能障礙.
목적 응용조직다보륵성상(TDI)기술검측Tei지수(TDI-Tei)급삼첨판배운동속도삼수,평개원발성고혈압병환자우심실공능적변화.방법 선취140례원발성고혈압병환자,기중좌심실비후(LVH)조69례,비좌심실비후(NLVH)조71례,령외선취정상건강자50례작위대조조.맥충다보륵측량삼첨판구서장조기혈류속도(E)、서장만기혈류속도(A),계산E/A비치；맥충TDI측량우심실측벽삼첨판배처적TDI-Tei급수축기봉치운동속도(Sm)、서장조기봉치운동속도(Em)、서장만기봉치운동속도(Am),계산Em/Am비치.결과 LVH조여NLVH조Em[(8.9±2.4)、(11.2±2.5)cm/s]、Em/Am비치[0.56±0.15、0.76±0.16]균명현저우대조조[분별위(13.1±3.2)cm/s、0.93±0.19],차이균유통계학의의(균P＜0.05).LVH조여NLVH조TDI-Tei(0.54±0.12、0.41 ±0.08)균명현고우대조조(0.33±0.06),차이유통계학의의(P＜0.05).LVH조Sm[( 12.3±2.3)cm/s]명현저우대조조[(13.8±2.3)cm/s],차이유통계학의의(P＜0.05).LVH조여NLVH조TDI-Tei여E/A비치、Em、Em/Am비치화Sm정명현부상관(분별위r=-0.412、r=-0.526、r=-0.498、r=-0.371,P＜0.01).결론 TDI-Tei연합삼첨판배운동속도삼수능구객관、전면지평개원발성고혈압병환자적우심실공능장애.
Objective To investigate the changes of right ventricular function in essential hypertension by pulse-wave tissue doppler imaging(TDI) and TDI-Tei index.Methods One hundred and forty elderly hypertensive patiens were divided into LVH group(69 patients with left ventricular hypertrophy)and NLVH group(71 patients without left ventricular hypertrophy).Control group consisted of 50 normal subjects.The index of echocardiography,including the tricuspid valve flow velocity during early and late diastole( E,A),ratio of E/A,peak velocities of RV lateral wall site at tricuspid annular during systole,early and late diastole (Sm,Em,Am),ratio of Em/Am and TDI-Tei were measured respectively.Results Compared with normal group,Em [( 8.9 ± 2.4) cm/s,( 11.2 ± 2.5)cm/s] and Em/Am(0.56 ± 0.15,0.76 ± 0.16)in LVH and NLVH groups were statistically different( P ＜ 0.05).TDI-Tei index(0.54 ±0.12,0.41 ±0.08)was statistically different( P ＜0.05).Compared with normalgroup[( 13.8 ± 2.3 ) cm/s],Sm of LVH group [( 12.3 ± 2.3 ) cm/s] was statistically different ( P ＜ 0.05 ).The TDI-Tei index was negatively correlated with E/A,Em,Em/Am and Sm ( r =-0.412,r =-0.526,r =-0.498,r =-0.371,all P ＜0.01 ).Conclusions TDI-Tei index,TDI-derived Sm,Em and Em/Am are valuable indexes to evaluate RV dysfunction in hypertension.
