中国实用护理杂志
中國實用護理雜誌
중국실용호리잡지
CHINESE JOURNAL OF PRACTICAL NURSING
2012年
20期
19-21
,共3页
杨瑞兰%任振环%任慧敏%李苗苗%毛巧玲%闫喜英%岳晓云
楊瑞蘭%任振環%任慧敏%李苗苗%毛巧玲%閆喜英%嶽曉雲
양서란%임진배%임혜민%리묘묘%모교령%염희영%악효운
硝酸甘油%单硝酸异山梨酯%冠心病%收缩压%舒张压
硝痠甘油%單硝痠異山梨酯%冠心病%收縮壓%舒張壓
초산감유%단초산이산리지%관심병%수축압%서장압
Nitroglycerin%Isesorbide mononitrate%Coronary heart disease%Systolic pressure%Diastolic pressure
目的 探讨静脉应用硝酸酯类治疗冠心病时不同给药速度与血压的关系,为临床制定适宜的给药速度提供依据.方法 收集应用硝酸酯类降压的冠心病患者155例,依据治疗药物的不同分为硝酸甘油组85例和单硝酸异山梨酯组70例.对2组患者均根据血压调整给药速度,观察并比较不同滴注速度时2组患者血压的变化.结果 以20滴/min的速度滴注时,2组间的收缩压和舒张压比较差异无统计学意义.而以30滴/min的速度滴注时,2组间的收缩压和舒张压比较差异均有统计学意义.硝酸甘油组不同滴速下的收缩压和舒张压均有显著的变化,而单硝酸异山梨酯组这种变化并不显著.硝酸甘油组9例用药过程中出现头痛.单硝酸异山梨酯组无头痛发生,2组血压升高.结论 静脉应用硝酸酯类药物以20 μg/min(相当于20滴/min)相对安全,再增加给药速度发生低血压的风险增加.单硝酸异山梨酯静脉滴注对血压影响较小.
目的 探討靜脈應用硝痠酯類治療冠心病時不同給藥速度與血壓的關繫,為臨床製定適宜的給藥速度提供依據.方法 收集應用硝痠酯類降壓的冠心病患者155例,依據治療藥物的不同分為硝痠甘油組85例和單硝痠異山梨酯組70例.對2組患者均根據血壓調整給藥速度,觀察併比較不同滴註速度時2組患者血壓的變化.結果 以20滴/min的速度滴註時,2組間的收縮壓和舒張壓比較差異無統計學意義.而以30滴/min的速度滴註時,2組間的收縮壓和舒張壓比較差異均有統計學意義.硝痠甘油組不同滴速下的收縮壓和舒張壓均有顯著的變化,而單硝痠異山梨酯組這種變化併不顯著.硝痠甘油組9例用藥過程中齣現頭痛.單硝痠異山梨酯組無頭痛髮生,2組血壓升高.結論 靜脈應用硝痠酯類藥物以20 μg/min(相噹于20滴/min)相對安全,再增加給藥速度髮生低血壓的風險增加.單硝痠異山梨酯靜脈滴註對血壓影響較小.
목적 탐토정맥응용초산지류치료관심병시불동급약속도여혈압적관계,위림상제정괄의적급약속도제공의거.방법 수집응용초산지류강압적관심병환자155례,의거치료약물적불동분위초산감유조85례화단초산이산리지조70례.대2조환자균근거혈압조정급약속도,관찰병비교불동적주속도시2조환자혈압적변화.결과 이20적/min적속도적주시,2조간적수축압화서장압비교차이무통계학의의.이이30적/min적속도적주시,2조간적수축압화서장압비교차이균유통계학의의.초산감유조불동적속하적수축압화서장압균유현저적변화,이단초산이산리지조저충변화병불현저.초산감유조9례용약과정중출현두통.단초산이산리지조무두통발생,2조혈압승고.결론 정맥응용초산지류약물이20 μg/min(상당우20적/min)상대안전,재증가급약속도발생저혈압적풍험증가.단초산이산리지정맥적주대혈압영향교소.
Objective To discuss the relationship of drip velocity of nitrate on blood pressure while treating coronary disease,in order to provide appropriate drip velocity for clinical treatment.Methods 155 patients with coronary disease using nitrate to lower blood pressure were selected.They were divided into the nitro glycerin group(85 cases) and the isosorbide mononitrate group( 70 cases) according to difference of medication.The velocity of drugs was adjusted on basis of blood pressure changes.The blood pressure changes at different drip velocities were observed and compared.Results The systolic pressure and the diastolic pressure between two groups showed no difference at 20 drops/min,but the results were the opposite at 30 drops/min.The systolic pressure and the diastolic pressure in the nitro glycerin group showed evident changes at different drip velocities,but in the isosorbide mononitrate group,these changes were not so significant.9 patients in the nitro glycerin group had headache during treatment,no headache occurred in the isosorbide mononitrate group.Conclusions Intravenous use of nitrate at a velocity of 20 drops/min is relative secure.The risk of hypotension will increase if the medication speed increases.lsosorbide mononitrate has little influence on blood pressure.
