CAJ | 학술논문

聚磷酸钙(Calcium polyphosphate,CPP)具有优异的生物相容性、生物活性、良好的骨传导性和可生物降解性,其钙磷比为0.5,是具有聚合重复单元的陶瓷基新型无机聚合生物材料,与骨组织有相似的化学成分.另外CPP降解后所释放的钙离子和磷酸根离子参与体内钙磷代谢,被重新沉积到骨组织中,可以加速骨组织矿化促进形成新骨,所以CPP作为一种新型的骨组织替代生物材料已成为研究的热点.详细介绍了CPP及其复合材料的制备、力学性能及生物学性能,对CPP的进一步研究和开发将赋予其更广阔的应用前景.
취린산개(Calcium polyphosphate,CPP)구유우이적생물상용성、생물활성、량호적골전도성화가생물강해성,기개린비위0.5,시구유취합중복단원적도자기신형무궤취합생물재료,여골조직유상사적화학성분.령외CPP강해후소석방적개리자화린산근리자삼여체내개린대사,피중신침적도골조직중,가이가속골조직광화촉진형성신골,소이CPP작위일충신형적골조직체대생물재료이성위연구적열점.상세개소료CPP급기복합재료적제비、역학성능급생물학성능,대CPP적진일보연구화개발장부여기경엄활적응용전경.
Calcium polyphosphate(CPP) has excellent biocompatibility, bioactivity, good bone conduction and biodegradability,and its calcium and phosphorus ratio is 0. 5, so CPP is a new ceramic inorganic polymer matrix bio-logical material with polymerizing repeated units, which has similar chemical composition with bone tissue. In addi-tion, the calcium and phosphate ions released from the degradation of CPP will participate calcium and phosphorus me-tabolism in the body, be re-deposited into bone tissue, accelerate the mineralization of bone tissue and promote the for-mation of new bone. Thereby CPP as a new type of biological material substituted for bone tissue has become a re-search hotspot. This paper clearly introduced the preparation, mechanical and biological properties of CPP and its composite materials. With further research and development, CPP will be given a wider application.