中国糖尿病杂志
中國糖尿病雜誌
중국당뇨병잡지
CHINESE JOURNAL OF DIABETES
2008年
3期
134-136
,共3页
韩轲%陈维清%黄杏端%文孝忠%谭华霖%谢兆丰
韓軻%陳維清%黃杏耑%文孝忠%譚華霖%謝兆豐
한가%진유청%황행단%문효충%담화림%사조봉
妊娠并发症%糖负荷异常
妊娠併髮癥%糖負荷異常
임신병발증%당부하이상
Glucose intolerance
目的 了解妊娠期糖代谢异常对孕妇和围生儿的影响.方法 对10809名孕妇在孕24~28周做50g葡萄糖负荷试验,阳性者再做75gOGTT,据血糖结果分为糖代谢正常(GNGT)组、妊娠糖尿病(GDM)组和妊娠期糖耐量减低(GIGT)组,比较三组妊娠的结局.结果 GDM和GIGT组的患病率分别为0.61%和2.50%.GDM组孕妇产后即时出血、剖宫产、妊娠高血压综合征、羊水过多、巨大儿、早产儿和新生儿低血糖的发生率均显著高于GNGT组;GIGT组剖宫产、羊水过多、巨大儿的发生率显著高于GNGT组,低体重儿发生率低于GNGT组.结论 妊娠期糖代谢异常对孕产妇和围生儿有不良影响,因此应重视孕期糖代谢异常的筛查、诊断和治疗.
目的 瞭解妊娠期糖代謝異常對孕婦和圍生兒的影響.方法 對10809名孕婦在孕24~28週做50g葡萄糖負荷試驗,暘性者再做75gOGTT,據血糖結果分為糖代謝正常(GNGT)組、妊娠糖尿病(GDM)組和妊娠期糖耐量減低(GIGT)組,比較三組妊娠的結跼.結果 GDM和GIGT組的患病率分彆為0.61%和2.50%.GDM組孕婦產後即時齣血、剖宮產、妊娠高血壓綜閤徵、羊水過多、巨大兒、早產兒和新生兒低血糖的髮生率均顯著高于GNGT組;GIGT組剖宮產、羊水過多、巨大兒的髮生率顯著高于GNGT組,低體重兒髮生率低于GNGT組.結論 妊娠期糖代謝異常對孕產婦和圍生兒有不良影響,因此應重視孕期糖代謝異常的篩查、診斷和治療.
목적 료해임신기당대사이상대잉부화위생인적영향.방법 대10809명잉부재잉24~28주주50g포도당부하시험,양성자재주75gOGTT,거혈당결과분위당대사정상(GNGT)조、임신당뇨병(GDM)조화임신기당내량감저(GIGT)조,비교삼조임신적결국.결과 GDM화GIGT조적환병솔분별위0.61%화2.50%.GDM조잉부산후즉시출혈、부궁산、임신고혈압종합정、양수과다、거대인、조산인화신생인저혈당적발생솔균현저고우GNGT조;GIGT조부궁산、양수과다、거대인적발생솔현저고우GNGT조,저체중인발생솔저우GNGT조.결론 임신기당대사이상대잉산부화위생인유불량영향,인차응중시잉기당대사이상적사사、진단화치료.
Objective To explore the adverse effect of abnormal metabolism of glucose during gestation on pregnant outcomes of pregnant women and peripartum babies. Methods 10 809 pregnant women at gestational age of 24~28 weeks were screened with 50g glucose challenge test (GCT), and subjects with a positive reaction would receive further 75g oral glucose tolerance test (OGTT).Based on the results of OGTT, they were divided into three groups: normal glucose tolerance(GNGT), gestational diabetes mellitus (GDM), and gestational impaired glucose tolerance (GIGT). Results Of 10 809 pregnant women, 66 women and 270 women were diagnosed as GDM (0.61%) and GIGT(2.5%), respectively.The incidences of postpartum hemorrhage, cesarean section, pregnancy-induced hypertension, polyhydramnios, fetal macrosomia, premature delivery, neonatal hypoglycemia were higher in GDM group than in GNGT group (P<0.05). The incidences of cesarean section, polyhydramnios and fetal acrosomia were higher in GIGT group than in GNGT group (P<0.05) .The incidence of low birth weight was lower in the GIGT group than in GNGT group (P<0.05) . Conclusions Abnormal metabolism of glucose in pregnancy can produce adverse impact on mothers and neonates.Therefore, it is very important to make detection, diagnosis and treatment for abnormality of glucose metabolism during pregnancy.