CAJ | 학술논문

目的观察墓头回总甙片治疗大肠癌的临床效果及配合化疗的增效减毒作用。方法 132例大肠癌患者随机分为化疗组、中药组、化疗十中药组，观察对比3组患者治疗前后的生活质量，近、远期疗效，机体免疫功能及CEA值的变化。客观评价墓头回总甙片对大肠癌的治疗作用。结果中药组及化疗十中药组患者生活质量较治疗前明显提高，患者的近期有效率、生存期以化疗十中药组变化最大，并能明显增强患者的免疫功能，减轻化疗对机体的损伤。结论墓头回总甙片是治疗大肠癌行之有效的药物，与化疗联用，可以提高临床效果，减轻化疗的副作用。
목적관찰묘두회총대편치료대장암적림상효과급배합화료적증효감독작용。방법 132례대장암환자수궤분위화료조、중약조、화료십중약조，관찰대비3조환자치료전후적생활질량，근、원기료효，궤체면역공능급CEA치적변화。객관평개묘두회총대편대대장암적치료작용。결과중약조급화료십중약조환자생활질량교치료전명현제고，환자적근기유효솔、생존기이화료십중약조변화최대，병능명현증강환자적면역공능，감경화료대궤체적손상。결론묘두회총대편시치료대장암행지유효적약물，여화료련용，가이제고림상효과，감경화료적부작용。
Objective　To observe the clinical efficacy of rad ix patriniae heterophylla glucoside tablets on colorectal cancer and its synergi sm with chemotherapy.Methods　132 colorectal cancer patients wer e randomly divided into three groups,treated respectively with chemotherapy alon e,traditional Chinese medicine alone,combination of chemotherapy and traditional Chinese medicine together.A comparative study was carried out including the lif e quality, the long-and short-term curative effect,organic immunological funct ion and changes of the CEA before and after the treatment.The curative effect o f radix patriniae heterophylla glucoside tablets on colorectal cancer w as objectively evaluated.Results　For the groups with traditiona l Chinese medicine and with chemotherapy plus traditional Chinese medicine,the l ife quality was greatly improved.The short-term effective rate and the survival time of the group with chemotherapy plus traditional Chinese medicine changed s ignificantly, which remarkably enhanced the immunological function and decreased the toxicity of chemotherapy.Conclusions　Radix patiriniae heter ophylla glucoside tablets are effective on colorectal cancer,especially when combined with chemotherapy.The tablets can increase the clinical efficacy a nd decrease the side effect of chemotherapy.