广州医学院学报
廣州醫學院學報
엄주의학원학보
ACADEMIC JOURNAL OF GUANGZHOU MEDICAL COLLEGE
2014年
1期
40-42
,共3页
血液透析%血红蛋白%继发性甲状旁腺功能亢进%铁蛋白
血液透析%血紅蛋白%繼髮性甲狀徬腺功能亢進%鐵蛋白
혈액투석%혈홍단백%계발성갑상방선공능항진%철단백
Hemodialysis%hemoglobin%secondary hyperparathyroidism%ferritin
目的：观察继发性甲状旁腺功能亢进在贫血的关系,探讨血液透析患者甲状旁腺素与血红蛋白水平的关系。方法：回顾性分析2010年3月至2012年12月广州医科大学第一附属医院收治的59例血液透析患者的资料,收取血液标本,检测血尿素氮( Bun)、肌酐、血红蛋白( Hb)、铁蛋白、全段甲状旁腺素(iPTH)。结果：Bun、肌酐、Hb、铁蛋白、iPTH分别为(26.3±5.5) mol/L、(834.2±125.4)μmol/L、(73.1±23.1) g/L、(665.3±552.2) ng/mL、(548.8±452.5) pg/mL； iPTH对Hb有显著性影响(χ2＝27.142, P<0.001)。 iPTH与Hb为负相关关系( r＝0.565)；iPTH与铁蛋白呈正相关关系( r＝0.070)。结论：血透患者贫血的发生与甲状旁腺功能亢进有关,有效控制SPHT有助贫血的治疗。
目的：觀察繼髮性甲狀徬腺功能亢進在貧血的關繫,探討血液透析患者甲狀徬腺素與血紅蛋白水平的關繫。方法：迴顧性分析2010年3月至2012年12月廣州醫科大學第一附屬醫院收治的59例血液透析患者的資料,收取血液標本,檢測血尿素氮( Bun)、肌酐、血紅蛋白( Hb)、鐵蛋白、全段甲狀徬腺素(iPTH)。結果：Bun、肌酐、Hb、鐵蛋白、iPTH分彆為(26.3±5.5) mol/L、(834.2±125.4)μmol/L、(73.1±23.1) g/L、(665.3±552.2) ng/mL、(548.8±452.5) pg/mL； iPTH對Hb有顯著性影響(χ2＝27.142, P<0.001)。 iPTH與Hb為負相關關繫( r＝0.565)；iPTH與鐵蛋白呈正相關關繫( r＝0.070)。結論：血透患者貧血的髮生與甲狀徬腺功能亢進有關,有效控製SPHT有助貧血的治療。
목적：관찰계발성갑상방선공능항진재빈혈적관계,탐토혈액투석환자갑상방선소여혈홍단백수평적관계。방법：회고성분석2010년3월지2012년12월엄주의과대학제일부속의원수치적59례혈액투석환자적자료,수취혈액표본,검측혈뇨소담( Bun)、기항、혈홍단백( Hb)、철단백、전단갑상방선소(iPTH)。결과：Bun、기항、Hb、철단백、iPTH분별위(26.3±5.5) mol/L、(834.2±125.4)μmol/L、(73.1±23.1) g/L、(665.3±552.2) ng/mL、(548.8±452.5) pg/mL； iPTH대Hb유현저성영향(χ2＝27.142, P<0.001)。 iPTH여Hb위부상관관계( r＝0.565)；iPTH여철단백정정상관관계( r＝0.070)。결론：혈투환자빈혈적발생여갑상방선공능항진유관,유효공제SPHT유조빈혈적치료。
Objective:To investigate the effects of secondary hyperparathyroidism ( SHPT) as a cause of anemia and the relationship of intact parathyroid hormone ( iPTH) and hemoglobin ( Hb) levels in patients receiving hemodialysis ( HD ) . Methods: Between March 2010 and December 2012, we did a retrospective analysis on the clinical profiles of 59 patients receiving hemodialysis from The First Affiliated Hospital of Guangzhou Medical University. Serum samples were collected for the measurement of urea, creatinine, Hb, ferritin and iPTH levels. Results:The levels of serum urea, creatinine, Hb, ferritin and intact PTH were (26.33 ±5.54)mol/L, (834.23±125.44)μmol/L, (73.1±23.1)g/L, (665.3±552.2)ng/ml and (548.78±452.54)pg/ml respectively. The level of iPTH had a considerable impact on the Hb (χ2=27.142, P<0.001) . The iPTH was negatively correlated with Hb (r=0.565, P<0.05) And positively correlated with ferritin (r=0.070, P<0.05). Conclusion: Secondary hyperparathyroidism ( SHPT ) may be a cause of anemia in patients receiving hemodialysis and an effective control of parathyroid hormone hypersecretion may be associated with alleviation of anemia.
