生殖与避孕(英文版)
生殖與避孕(英文版)
생식여피잉(영문판)
REPRODUCTION & CONTRACEPTION
2002年
2期
74-83
,共10页
杨婕%桂幼伦%郑娥香%贺昌海
楊婕%桂幼倫%鄭娥香%賀昌海
양첩%계유륜%정아향%하창해
mifepristone%misoprostol%late luteal fertility regulation
Objective To investigate the efficacy, safety and acceptability of mifepristone com-bined with misoprostol used for late luteal fertility regulationtreatment cycles in total. Subjects were planned to receive treatment with 25 mg ofmifepristone, Q12 h × 4 orally for five days prior to expected menstruation followedby 400 μg of misoprostol 48 h later for up to six cycles.Results There were 13 pregnancies in the 267 treatment cycles and among them com-plete abortion and continuing pregnancy occurred in 7 and 6 cycles respectively. So theoverall pregnancy rate was 4. 87% (13/267) and the rate of continuing pregnancywas 2. 25% (6/267), while the failure rate per pregnant cycle was 46. 15% (6/13).In treatment cycles the vaginal bleeding patterns changed insignificantly as comparedwith those in control cycles.Conclusion The efficacy, compliance and acceptability of the regimen should befurther improved when it was administered for late luteal fertility regulation.
