国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2010年
4期
435-438
,共4页
气管导管%生物被膜%呼吸机相关肺炎
氣管導管%生物被膜%呼吸機相關肺炎
기관도관%생물피막%호흡궤상관폐염
Endotracheal tube%Biofilm%Ventilator associatcd pneumonia
呼吸机相关肺炎(VAP)是机械通气患者常见并发症,是导致其病死率、住院时间、住院费用增加的主要原因.虽然VAP的诊断技术和抗生素应用不断进展,但VAP的发病率、病死率并无明显下降.因此,从发病机制入手探讨VAP防治策略在临床工作中显得尤为重要.近年研究报道生物被膜的形成是VAP的重要发病机制.
呼吸機相關肺炎(VAP)是機械通氣患者常見併髮癥,是導緻其病死率、住院時間、住院費用增加的主要原因.雖然VAP的診斷技術和抗生素應用不斷進展,但VAP的髮病率、病死率併無明顯下降.因此,從髮病機製入手探討VAP防治策略在臨床工作中顯得尤為重要.近年研究報道生物被膜的形成是VAP的重要髮病機製.
호흡궤상관폐염(VAP)시궤계통기환자상견병발증,시도치기병사솔、주원시간、주원비용증가적주요원인.수연VAP적진단기술화항생소응용불단진전,단VAP적발병솔、병사솔병무명현하강.인차,종발병궤제입수탐토VAP방치책략재림상공작중현득우위중요.근년연구보도생물피막적형성시VAP적중요발병궤제.
Ventilator associatcd pneumonia (VAP) is the common complication in patients with machinecal ventilation as well as the main causes due to the increase of fatality rate,length and cost of hospitalization.The diagnostic techniques of VAP and the utilizations of antibiotics have developed,but incidence rate and fatality rate have not descended obviously.So it is important to probe the methods of prevention and cure VAP from the pathogenesis.It is reported recently that the formation of biofilm is one of the important causes of VAP.The review about the relations between VAP and the formation of bacterial biofilm is followed.