CAJ | 학술논문

目的探讨皮肤恶性肿瘤的临床特点.方法回顾2005-2008年病理诊断皮肤恶性肿瘤及癌前病变的病例资料,重新阅片确认肿瘤诊断和病理亚型分型后,利用统计软件进行分析.结果基底细胞癌及原位和侵袭性鳞状细胞癌最多见,分别占总病例数的29.3%及24.2%.在所研究病例中,>60岁发病者占55.4%,35～59岁发病比例达到34.3%,青少年患者比例为10.3%.Paget病临床诊断与病理诊断的符合率接近90.0%,但其他常见皮肤恶性肿瘤及癌前病变临床与病理的符合率仅在70.0%左右.结论在皮肤恶性肿瘤及癌前病变中,头面部皮肤肿瘤及癌前病变病例明显多于其他部位.中青年患者不仅在皮肤淋巴瘤相关肿瘤病例中多见,而且在上皮来源的皮肤恶性肿瘤及黑素瘤病例中占有显著比例.
목적 탐토피부악성종류적림상특점.방법 회고2005-2008년병리진단피부악성종류급암전병변적병례자료,중신열편학인종류진단화병리아형분형후,이용통계연건진행분석.결과 기저세포암급원위화침습성린상세포암최다견,분별점총병례수적29.3%급24.2%.재소연구병례중,>60세발병자점55.4%,35～59세발병비례체도34.3%,청소년환자비례위10.3%.Paget병림상진단여병리진단적부합솔접근90.0%,단기타상견피부악성종류급암전병변림상여병리적부합솔부재70.0%좌우.결론 재피부악성종류급암전병변중,두면부피부종류급암전병변병례명현다우기타부위.중청년환자불부재피부림파류상관종류병례중다견,이차재상피래원적피부악성종류급흑소류병례중점유현저비례.
Objective To investigate the clinical features of skin cancer.Methods Clinical data of skin cancer and precancerous skin lesions confirmed pathologically from 2005 to 2008 in Peking University First Hospital were retrospectively analyzed by using statistical methods.Results A total of 632 cases of skin cancer and precancerous skin lesions were studied.The most common skin cancer was basal cell carcinoma and squamous cell carcinoma (invasive and in situ) which accounted for 29.3%and 24.2%,respectively.The average age at onset was older than 60 years in 55.4%of the patients,between 35 and 59 years in 34.3%,younger than 35 years in 10.3%.The concordance between clinical and pathological diagnosis reached nearly 90.O%for Paget's disease,70.0% for other common skin cancer and precancerous skin lesions.Conclusions Skin cancer and precancerous skin lesions have a predilection for scalp and face.Patients aged from 35 to 59 years account for a significant proportion not only in cutaneous lymphoma but also in melanoma and epithelium-derived nonmelanoma skin cancer.