CAJ | 학술논문

目的研究准分子激光前弹力层下角膜磨镶术(SBK)矫正屈光不正手术前后的散射特征,并分析其相关因素.方法前瞻性临床研究.行SBK手术的近视及近视散光患者46例(92眼),男29例,女17例,年龄18～39岁,平均(24.0±5.4)岁；等效球镜度为-4.75～-11.13 D,平均(-6.70±1.50)D；散光度为0～2.50 D,平均(0.68±0.58)D.手术前,采用Pentacam眼前节分析仪测量平均曲率值、角膜中央厚度等.手术前及手术后第1天、第1周、第1个月,应用C-Quant散射光计量仪测量患者的散射值.对所得数据分别应用重复测量的方差分析、配对t检验及Pearson相关进行分析.结果 SBK手术前眼内散射光计量值平均为0.90±0.13,手术后第1天、第1周、第1个月眼内散射光计量值分别为0.96±0.13、0.98±0.10、0.99±0.09,与术前比较,术后各个随访时间点散射均增加(F=24.94,P＜0.05).经Pearson相关分析,手术前散射光计量值与等效球镜度、平均曲率值、角膜中央厚度的相关性无统计学意义；手术后各时间点散射光计量值增加量与术前散射光计量值水平呈负相关(r=-0.47、-0.67、-0.78,P均＜0.05),与术前等效球镜度、切削深度的相关性无统计学意义.结论 SBK术后早期散射增加可能是影响视觉质量的因素之一,术前散射光计量值愈低的患者术后增加量愈明显.
목적 연구준분자격광전탄력층하각막마양술(SBK)교정굴광불정수술전후적산사특정,병분석기상관인소.방법 전첨성림상연구.행SBK수술적근시급근시산광환자46례(92안),남29례,녀17례,년령18～39세,평균(24.0±5.4)세；등효구경도위-4.75～-11.13 D,평균(-6.70±1.50)D；산광도위0～2.50 D,평균(0.68±0.58)D.수술전,채용Pentacam안전절분석의측량평균곡솔치、각막중앙후도등.수술전급수술후제1천、제1주、제1개월,응용C-Quant산사광계량의측량환자적산사치.대소득수거분별응용중복측량적방차분석、배대t검험급Pearson상관진행분석.결과 SBK수술전안내산사광계량치평균위0.90±0.13,수술후제1천、제1주、제1개월안내산사광계량치분별위0.96±0.13、0.98±0.10、0.99±0.09,여술전비교,술후각개수방시간점산사균증가(F=24.94,P＜0.05).경Pearson상관분석,수술전산사광계량치여등효구경도、평균곡솔치、각막중앙후도적상관성무통계학의의；수술후각시간점산사광계량치증가량여술전산사광계량치수평정부상관(r=-0.47、-0.67、-0.78,P균＜0.05),여술전등효구경도、절삭심도적상관성무통계학의의.결론 SBK술후조기산사증가가능시영향시각질량적인소지일,술전산사광계량치유저적환자술후증가량유명현.
Objective To investigate the characteristics and relevant factors of intraocular straylight before and after sub-Bowman's keratomileusis (SBK).Methods This was a prospective clinical study.Straylight measurement was performed on 46 myopic and myopic astigmatism patients (92 eyes) before SBK surgery and 1 day,1 week,and 1 month after surgery using Oculus C-Quant straylight meter.In 46 patients,there were 29 males and 17 females,the mean age was (24.0±5.4)years (range: 18 to 39 years),and the mean preoperative spherical equivalent (SE) of refraction was (-6.70±1.50)D (range:-11.13 to -4.75 D),with mean astigmatism of (0.68±0.58)D (range:0 to 2.50 D).The mean keratometric value and central corneal thickness (CCT) were tested by Pentacam device.The data was analyzed for statistical significance by repeated measure ANOVA,paired t tests and Pearson correlation using SPSS 13.0 software.Results Patients had a mean straylight of logarithmic value of the straylight parameter [log(s)]=(0.90±0.13) before surgery,which showed no significant correlation with spherical equivalent (SE),keratometric (K) value,and CCT.After surgery,the mean straylight of [log(s)]=0.96±0.13,0.98±0.10,and 0.99±0.09 at 1 day,1 week,and 1 month postoperatively respectively.When comparing with preoperative straylight values,the difference did reach a statistical significance increase for various time points after SBK (F=24.94,P＜0.05).The individual postop-preop changes in straylight showed significant negative correlation with the preoperative values (r=-0.47,-0.67,-0.78,P＜0.05),and showed no significant relationship with intended refractive correction and ablation depth.Conclusion Straylight values increases significantly at early time after SBK,which maybe influence visual performance at this time.Patients with lower preoperative straylight values present exacerbated elevation after SBK.