CAJ | 학술논문

目的探讨儿童肠道病毒71型(EV71)感染的临床特征.方法回顾性分析我院2008年4月至7月间18例EV71感染病例的流行病学特征及临床表现.结果发病年龄以3岁以下为主(89%),外地移居儿童发病率明显高于本地儿童.所有患儿均出现发热及皮疹(100%),合并肺炎5例(28%),肺水肿并肺出血2例(11%),心肌炎5例(28%),病毒性脑炎4例(22%).治愈13例,好转2例,自动出院1例,死亡2例.结论重症病例主要由EV71感染引起;肢体抖动、膝反射亢进是重症病例较具特征的表现;白细胞增高、血糖升高对危重病例的早期发现有提示意义.
목적 탐토인동장도병독71형(EV71)감염적림상특정.방법 회고성분석아원2008년4월지7월간18례EV71감염병례적류행병학특정급림상표현.결과 발병년령이3세이하위주(89%),외지이거인동발병솔명현고우본지인동.소유환인균출현발열급피진(100%),합병폐염5례(28%),폐수종병폐출혈2례(11%),심기염5례(28%),병독성뇌염4례(22%).치유13례,호전2례,자동출원1례,사망2례.결론 중증병례주요유EV71감염인기;지체두동、슬반사항진시중증병례교구특정적표현;백세포증고、혈당승고대위중병례적조기발현유제시의의.
Objective To study the clinical characteristics of enterovirus 71 infection in children. Methods A retrospective analysis was conducted to study the enterovirus 71 infection prevalence and clini-cal characteristics of our hospital during the period from April to July 2008. Results The onset age of most cases (89%) was below 3 years. Migrant children showed higher incidence than local children. All children had fever and skin rash (100%),5 cases were combined with pneumonia (28%),2 cases with pulmonary e-dema and pulmonary hemorrhage (11%) ,5 cases with myocarditis (28%) ,4 cases with viral encephalitis (22%). 13 cases were cured,2 cases showed improved signs and symptoms of enterovirus 71 infection, 1 case quitted and 2 cases died. Conclusion Severe cases are mainly caused by enterovirus 71. Jitter limbs and knee jerk hyperreflexia are characteristic in severe cases;higher WBC count and blood glucose rise are indica-tive for severe cases.