中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2009年
52期
10263-10268
,共6页
张国栋%廖维靖%陶圣祥%毛文玉%陈建桥%郑晓晖%牛素生
張國棟%廖維靖%陶聖祥%毛文玉%陳建橋%鄭曉暉%牛素生
장국동%료유정%도골상%모문옥%진건교%정효휘%우소생
股骨颈%三维重建%有限元%材料属性%有效性验证%数字化医学
股骨頸%三維重建%有限元%材料屬性%有效性驗證%數字化醫學
고골경%삼유중건%유한원%재료속성%유효성험증%수자화의학
背景:作者前期实验通过理论推导的方式,认为将骨骼材料属性分为10种即可达到有限元分析的要求,其结论是否与真实相符,有待于与体外力学实验结果进行对比验让.目的:对12侧股骨上段标本进行有限元分析,并与体外力学试验结果对比验证,以探讨骨骼合理的赋材料属性方法.方法:将12侧股骨上段标本进行高速CT薄层扫描,在Mimics中进行三维重建,在Ansys中进行体网格划分.有限元分析组在Mimics中根据灰度值将三维模型材料属性分为2种(密质骨及松质骨)、10,50,100,200,400种后赋予材料属性,在Ansys中进行力学分析并采集股骨颈表面节点力学数值.体外力学实验组将12侧股骨上段标本进行压缩实验,采集与有限元分析组相同的测试点力学数据.结果与结论:单因素方差分析显示,力学实验组与有限元分析2种材料属性组比较,差异无显著性意义(P=0.082);与有限元分析10,50,100,200,400种材料属性组比较,差异无显著性意义(P>0.39).有限元分析各亚组中,2种材料属性组与其余各组比较,差异有显著性意义(P<0.05),10,50,100,200,400种材料属性组间比较,差异无显著性意义(P>0.9).结果提示,赋予骨骼10种材料属性即可达到有限元分析的要求.
揹景:作者前期實驗通過理論推導的方式,認為將骨骼材料屬性分為10種即可達到有限元分析的要求,其結論是否與真實相符,有待于與體外力學實驗結果進行對比驗讓.目的:對12側股骨上段標本進行有限元分析,併與體外力學試驗結果對比驗證,以探討骨骼閤理的賦材料屬性方法.方法:將12側股骨上段標本進行高速CT薄層掃描,在Mimics中進行三維重建,在Ansys中進行體網格劃分.有限元分析組在Mimics中根據灰度值將三維模型材料屬性分為2種(密質骨及鬆質骨)、10,50,100,200,400種後賦予材料屬性,在Ansys中進行力學分析併採集股骨頸錶麵節點力學數值.體外力學實驗組將12側股骨上段標本進行壓縮實驗,採集與有限元分析組相同的測試點力學數據.結果與結論:單因素方差分析顯示,力學實驗組與有限元分析2種材料屬性組比較,差異無顯著性意義(P=0.082);與有限元分析10,50,100,200,400種材料屬性組比較,差異無顯著性意義(P>0.39).有限元分析各亞組中,2種材料屬性組與其餘各組比較,差異有顯著性意義(P<0.05),10,50,100,200,400種材料屬性組間比較,差異無顯著性意義(P>0.9).結果提示,賦予骨骼10種材料屬性即可達到有限元分析的要求.
배경:작자전기실험통과이론추도적방식,인위장골격재료속성분위10충즉가체도유한원분석적요구,기결론시부여진실상부,유대우여체외역학실험결과진행대비험양.목적:대12측고골상단표본진행유한원분석,병여체외역학시험결과대비험증,이탐토골격합리적부재료속성방법.방법:장12측고골상단표본진행고속CT박층소묘,재Mimics중진행삼유중건,재Ansys중진행체망격화분.유한원분석조재Mimics중근거회도치장삼유모형재료속성분위2충(밀질골급송질골)、10,50,100,200,400충후부여재료속성,재Ansys중진행역학분석병채집고골경표면절점역학수치.체외역학실험조장12측고골상단표본진행압축실험,채집여유한원분석조상동적측시점역학수거.결과여결론:단인소방차분석현시,역학실험조여유한원분석2충재료속성조비교,차이무현저성의의(P=0.082);여유한원분석10,50,100,200,400충재료속성조비교,차이무현저성의의(P>0.39).유한원분석각아조중,2충재료속성조여기여각조비교,차이유현저성의의(P<0.05),10,50,100,200,400충재료속성조간비교,차이무현저성의의(P>0.9).결과제시,부여골격10충재료속성즉가체도유한원분석적요구.
BACKGROUND:Based on previously theoretical derivation,it thought that assignment with 10 kinds of material attributes to three-dimensional model of bone can match the needs of finite element analysis,however,whether the results is consistent with actual needs to be validated by experimental results.OBJECTIVE:Twelve specimens of femoral superior segment were used for finite element analysis,which were verified with results of biomechanical testing,to explore a reasonable method for material assignment of bone.METHODS:All 12 specimens of femoral superior segment were treated with CT scan,three-dimensional reconstruction in Mimics 10.0 and volume meshing in Ansys.The finite element analysis group was divided into 2 kinds (compact bone and cancellated bone),10,50,100,200,400 kinds of material attributes groups based on the gray value.All models were assigned with material attributes and tested in Ansys for mechanics data of nodes on surface of femoral neck.In biomechanical testing group,12 specimens of femoral superior segment were treated with compressed testing to harvest mechanics data of measuring point same as that of finite element analysis group.RESULTS AND CONCLUSION:The one-way analysis of variance showed that the differences between the biomechanical testing group and finite element analysis group of 2 kinds of material attributes had no obvious significance (P=0.082).Compared to the 10,50,100,200,400 kinds of material attributes group,the difference had no significance (P > 0.39).However,the differences between the 2 kinds of material attributes and the 10,50,100,200,400 kinds of material attributes in the finite element analysis group were obviously difference (P< 0.05),which was no difference in the 10,50,100,200,400 kinds of material attributes (P>0.9).The results demonstrated that to assign 10 kinds of material attributes to three-dimensional model of bone can match the needs of finite element analysis.