CAJ | 학술논문

神经血管单元(neurovascular unit,NVU)由神经元、胶质细胞和微血管等构成,各细胞成分之间存在复杂的相互作用,构成协调统一的整体.脑缺血时,NVU各组成成分间信号传递发生障碍,导致神经元和细胞外基质破坏,进而发生脑梗死和出血性转化.因此,缺血性卒中的治疗应以保护NVU的整体功能为基础.文章阐述了脑缺血后NVU的变化和保护.
신경혈관단원(neurovascular unit,NVU)유신경원、효질세포화미혈관등구성,각세포성분지간존재복잡적상호작용,구성협조통일적정체.뇌결혈시,NVU각조성성분간신호전체발생장애,도치신경원화세포외기질파배,진이발생뇌경사화출혈성전화.인차,결혈성졸중적치료응이보호NVU적정체공능위기출.문장천술료뇌결혈후NVU적변화화보호.
The neurovascular unit (NVU) consists of neurons,gllal cells and microvessels,etc.There were complex interactions among the various cellular components,which form as a uniform entirety preferably.Anong the various cellular components of NVU,the signal transduction occurred disorders during cerebral ischemia,resulting in neuronal and extracellular ratrix destruction,and thus occurring cerebral infarction and hemorrhagic transformation.Therefore,the treatment of ischemic sttroke should be based on the protection of the overall function of NVU.This article describes the changes and protection of NVU after cerebral ischemia.