中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2012年
1期
1-5
,共5页
所世腾%朱善宝%陈亚珠%李跃华%张素
所世騰%硃善寶%陳亞珠%李躍華%張素
소세등%주선보%진아주%리약화%장소
核磁共振成像%弥散加权成像%弥散峰度成像%卒中
覈磁共振成像%瀰散加權成像%瀰散峰度成像%卒中
핵자공진성상%미산가권성상%미산봉도성상%졸중
Magnetic resonance imaging%Diffusion weighted imaging%Diffuse kurtosis imaging%Stroke
目的 研究弥散峰度成像(DKI)对脑组织灰质和白质的描述以及在脑中风诊断中的应用.方法 采用2例正常人以及15例脑中风患者(包含9例脑梗死,急性、亚急性和陈旧性各占3例)的脑部核磁共振图像作为试验数据.针对每例数据各个像素位置,分别对9个不同弥散梯度场下各个信号强度进行非线性拟合得到弥散系数(D值)和弥散峰度(K值),进而做出ADC图和DKI图.观察比较分析各例在ADC图和DKI图的表现.结果 DKI成像具有更多的纹理细节,包含更丰富的组织特征.急性、亚急性脑梗死病灶在DKI图呈现高信号,陈旧性脑梗死病灶在DKI图呈现低信号,平均峰度相对值(rMK)分别为2.193±0.166,1.789±0.162,0.564±0.069.结论 DKI对脑组织尤其是灰质以及一些脑中风病灶的描述相对于ADC图包含更多的组织信息.脑梗死病灶的rMK值具有特征性演变规律.
目的 研究瀰散峰度成像(DKI)對腦組織灰質和白質的描述以及在腦中風診斷中的應用.方法 採用2例正常人以及15例腦中風患者(包含9例腦梗死,急性、亞急性和陳舊性各佔3例)的腦部覈磁共振圖像作為試驗數據.針對每例數據各箇像素位置,分彆對9箇不同瀰散梯度場下各箇信號彊度進行非線性擬閤得到瀰散繫數(D值)和瀰散峰度(K值),進而做齣ADC圖和DKI圖.觀察比較分析各例在ADC圖和DKI圖的錶現.結果 DKI成像具有更多的紋理細節,包含更豐富的組織特徵.急性、亞急性腦梗死病竈在DKI圖呈現高信號,陳舊性腦梗死病竈在DKI圖呈現低信號,平均峰度相對值(rMK)分彆為2.193±0.166,1.789±0.162,0.564±0.069.結論 DKI對腦組織尤其是灰質以及一些腦中風病竈的描述相對于ADC圖包含更多的組織信息.腦梗死病竈的rMK值具有特徵性縯變規律.
목적 연구미산봉도성상(DKI)대뇌조직회질화백질적묘술이급재뇌중풍진단중적응용.방법 채용2례정상인이급15례뇌중풍환자(포함9례뇌경사,급성、아급성화진구성각점3례)적뇌부핵자공진도상작위시험수거.침대매례수거각개상소위치,분별대9개불동미산제도장하각개신호강도진행비선성의합득도미산계수(D치)화미산봉도(K치),진이주출ADC도화DKI도.관찰비교분석각례재ADC도화DKI도적표현.결과 DKI성상구유경다적문리세절,포함경봉부적조직특정.급성、아급성뇌경사병조재DKI도정현고신호,진구성뇌경사병조재DKI도정현저신호,평균봉도상대치(rMK)분별위2.193±0.166,1.789±0.162,0.564±0.069.결론 DKI대뇌조직우기시회질이급일사뇌중풍병조적묘술상대우ADC도포함경다적조직신식.뇌경사병조적rMK치구유특정성연변규률.
Objective To investigate diffuse kurtosis imaging (DKI) in the description of cerebral white and grey matter and application for diagnosis of stroke.Methods The profiles of cerebral magnetic resonance imaging (MRI) in 2 normal controls and 15 patients with stroke (9 with cerebral infarction,including 3 respective cases of acute,subacute and old infarction) were analyzed. Diffusion coefficient (D value) and diffusion kurtosis (K value) of each signal were obtained via nonlinear fitting corresponding to the location of individual pixel in 9 diffusion gradient fields for depiction of ADC and DKI maps.The images of ADC and DKI maps were studied and compared.Results DKI map contained more texture details and abundant tissue characters.Acute and subacute cerebral infarction presented hyperintensity signals in DKI,while old infarction presented hypointensity signals,with mean relative MK value (rMK) of (2.193±0.166),(1.789 ± 0.162) and (0.564± 0.069),respectively.Conclusion DKI offers more information of brain tissue,particularly in terms of grey matter and stroke foci,as compared with ADC that mainly focuses in tissues.Features of variation in rMK value of cerebral infarction can be captured.
