中华胃肠外科杂志
中華胃腸外科雜誌
중화위장외과잡지
CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
2009年
1期
65-68
,共4页
薛利军%尹路%周慧江%张贵阳%林谋斌%倪俊声%金志明%彭承宏%李宏为
薛利軍%尹路%週慧江%張貴暘%林謀斌%倪俊聲%金誌明%彭承宏%李宏為
설리군%윤로%주혜강%장귀양%림모빈%예준성%금지명%팽승굉%리굉위
大鼠%小肠移植,原位%外科手术%并发症
大鼠%小腸移植,原位%外科手術%併髮癥
대서%소장이식,원위%외과수술%병발증
Rat%Intestinal transplantation,orthotopic%Surgical procedure%Complication
目的 探讨大鼠原位小肠移植术的手术技巧及常见并发症的处理和预防.方法 用改进的三袖套法对120只大鼠进行原位小肠移植术.总结手术技巧,分析常见并发症的发生原因及相应的处理和预防措施.结果 术后有99只大鼠(82.5%)生存超过1周,死亡21只.受体术中出血平均少于1 ml.导致大鼠死亡的原因为术中吻合口大出血(5只,4.2%)、门静脉血栓形成(2只,1.7%)、门静脉大量空气栓塞(1只,0.8%)、动脉血栓形成(4只,3.3%)、吸人性肺炎(2只,1.7%)、感染(4只,3.3%)、麻醉意外(2只,1.7%)和肠扭转(1只,0.8%).结论 娴熟细致的外科操作、熟悉各种并发症的原因并采取相应的措施可有效提高手术成功率.
目的 探討大鼠原位小腸移植術的手術技巧及常見併髮癥的處理和預防.方法 用改進的三袖套法對120隻大鼠進行原位小腸移植術.總結手術技巧,分析常見併髮癥的髮生原因及相應的處理和預防措施.結果 術後有99隻大鼠(82.5%)生存超過1週,死亡21隻.受體術中齣血平均少于1 ml.導緻大鼠死亡的原因為術中吻閤口大齣血(5隻,4.2%)、門靜脈血栓形成(2隻,1.7%)、門靜脈大量空氣栓塞(1隻,0.8%)、動脈血栓形成(4隻,3.3%)、吸人性肺炎(2隻,1.7%)、感染(4隻,3.3%)、痳醉意外(2隻,1.7%)和腸扭轉(1隻,0.8%).結論 嫻熟細緻的外科操作、熟悉各種併髮癥的原因併採取相應的措施可有效提高手術成功率.
목적 탐토대서원위소장이식술적수술기교급상견병발증적처리화예방.방법 용개진적삼수투법대120지대서진행원위소장이식술.총결수술기교,분석상견병발증적발생원인급상응적처리화예방조시.결과 술후유99지대서(82.5%)생존초과1주,사망21지.수체술중출혈평균소우1 ml.도치대서사망적원인위술중문합구대출혈(5지,4.2%)、문정맥혈전형성(2지,1.7%)、문정맥대량공기전새(1지,0.8%)、동맥혈전형성(4지,3.3%)、흡인성폐염(2지,1.7%)、감염(4지,3.3%)、마취의외(2지,1.7%)화장뉴전(1지,0.8%).결론 한숙세치적외과조작、숙실각충병발증적원인병채취상응적조시가유효제고수술성공솔.
Objective To investigate operative techniques, treatment and precaution of common complications of orthotopic intestinal transplantation in the rats. Methods Orthotopic intestinal transplantation was performed in 120 rats by modified three cuffs method. The causes, treatment and precaution of common complications were analyzed retrospectively. Results The 7-day survival rate of recipients was 82.5% and the 30-day survival rate was 68.3%. The average volume of bleeding in the recipient operation was less than 1 ml.The result obtained from the above 99 recipients was satisfactory. The main reasons of final failure and death were as follows:anastomotic bleeding (5 rats), portal vein thrombus (2 rats),arterial thrombus (4 rots),air embolism (1 rat), infection of abdominal cavity(4 rats), aspiration pneumonitis (2 rots), anesthetic accident(2 rats) and kinking of graft intestine (1 rats). Conclusions The sophisticated surgical technique and the delicate surgical manipulation are the prerequisite of preventing operational complication. Improving operative techniques and being familiar with the common complications can reduce the occurrence of complications and increase operative successful rate.