解剖学报
解剖學報
해부학보
ACTA ANATOMICA SINICA
2010年
2期
323-325
,共3页
肝星形细胞%肝再生%肝纤维化%细胞分离鉴定
肝星形細胞%肝再生%肝纖維化%細胞分離鑒定
간성형세포%간재생%간섬유화%세포분리감정
Hepatic stellate cell%Liver regeneraion%Hepatofibrosis%Cell isolation and identification
肝星形细胞(HSCs)是肝脏中具有储存脂质特别是维生素A、合成细胞外基质、调节肝窦微循环等功能的非肝实质细胞,它们与多种肝脏疾病,特别是肝纤维化密切相关.我们简要总结了近几年有关肝星形细胞的分离、鉴定、增殖及增殖调控、在肝再生、肝病等中作用的研究进展.
肝星形細胞(HSCs)是肝髒中具有儲存脂質特彆是維生素A、閤成細胞外基質、調節肝竇微循環等功能的非肝實質細胞,它們與多種肝髒疾病,特彆是肝纖維化密切相關.我們簡要總結瞭近幾年有關肝星形細胞的分離、鑒定、增殖及增殖調控、在肝再生、肝病等中作用的研究進展.
간성형세포(HSCs)시간장중구유저존지질특별시유생소A、합성세포외기질、조절간두미순배등공능적비간실질세포,타문여다충간장질병,특별시간섬유화밀절상관.아문간요총결료근궤년유관간성형세포적분리、감정、증식급증식조공、재간재생、간병등중작용적연구진전.
Hepatic stellate cells (HSCs) are a group of nonparenchymal cells of liver, and play an important role in lipid, especially vitamin A-storing, extracellular matrix synthesis, microcirculation regulation of hepatic sinusoid, etc. They are also closely related to lots of liver diseases, e. g. hepatofibrosis. In this review, the latest research advance on HSCs including their isolation, identification, proliferation and regulation, and role in liver regeneration, hepatofibrosis, and so on is summarized.
